Product Information
IBUPROFEN 400 MG TABLET is a generic product labeled by Exelan Pharmaceuticals Inc., priced at $0.0391 per EA under NDC 76282071246. Its NADAC has been published 90 times since Dec 4, 2024.
FDA first approved this application on Sep 15, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 mg/1
Manufacturer
Exelan Pharmaceuticals Inc.NDC
76282071246
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
IBUPROFENApproval Type
Generic (ANDA)
FDA Application
ANDA091625FDA Approved
9/15/2015
TE Code
AB
On Market Since
3/10/2022
Pharmacological Classes
Price Statistics
The NADAC for IBUPROFEN 400 MG TABLET has been published 90 times since Dec 4, 2024, and over the history we have for it it has risen 15.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0391 per EA |
|---|---|
| All-time high | $0.0450 (May 14, 2025) |
| All-time low | $0.0338 (Dec 4, 2024) |
| 52-week high | $0.0433 |
| 52-week low | $0.0387 |
| Median price | $0.0412 |
| Average price | $0.0413 |
| Largest weekly change | +15.8% (Dec 18, 2024) |
| Weeks tracked | 90 |
| Tracking since | Dec 4, 2024 |
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of IBUPROFEN 400 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for IBUPROFEN 400 MG TABLET, manufactured by Exelan Pharmaceuticals Inc., is $0.0391 per EA (NDC 76282071246), effective Aug 19, 2026.
How has the price of IBUPROFEN 400 MG TABLET changed over time?
Over the history we have for it, the NADAC for IBUPROFEN 400 MG TABLET has risen 15.8%. It has been tracked across 90 weekly CMS publications since Dec 4, 2024.
What are the highest and lowest recorded NADAC prices for IBUPROFEN 400 MG TABLET?
Since Dec 4, 2024, the NADAC for IBUPROFEN 400 MG TABLET has ranged from a low of $0.0338 (Dec 4, 2024) to a high of $0.0450 (May 14, 2025), with a median of $0.0412 per EA.
Are there cheaper alternatives to IBUPROFEN 400 MG TABLET?
14 manufacturers publish a NADAC-priced product with the same active ingredient and strength as IBUPROFEN 400 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures IBUPROFEN 400 MG TABLET?
IBUPROFEN 400 MG TABLET (NDC 76282071246) is labeled by Exelan Pharmaceuticals Inc., and CMS classifies it as a generic product.