This NDC is on FDA's drug shortage list (posted Mar 1, 2017)
Reported reason: Demand increase for the drug
Product Information
SODIUM BICARB 8.4% SYRINGE is a generic product labeled by International Medication Systems, Limited, priced at $0.3288 per ML under NDC 76329335201. Its NADAC has been published 165 times since Apr 22, 2015.
FDA first approved this application on Sep 19, 2017. Its Orange Book therapeutic-equivalence code is AP.
Strength
84 mg/mL
Manufacturer
International Medication Systems, LimitedNDC
76329335201
Classification
Generic
Dosage Form
INJECTION
Route
INTRAVENOUS
Effective Date
12/18/2024
Active Ingredients
SODIUM BICARBONATEApproval Type
Generic (ANDA)
FDA Application
ANDA203449FDA Approved
9/19/2017
TE Code
AP
On Market Since
6/1/2000
Price Statistics
The NADAC for SODIUM BICARB 8.4% SYRINGE has been published 165 times since Apr 22, 2015, and over the history we have for it it has risen 177.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3288 per ML |
|---|---|
| All-time high | $0.3288 (Dec 10, 2025) |
| All-time low | $0.1186 (Apr 22, 2015) |
| 52-week high | $0.3288 |
| 52-week low | $0.3288 |
| Median price | $0.1489 |
| Average price | $0.2159 |
| Largest weekly change | +117.0% (Aug 21, 2024) |
| Weeks tracked | 165 |
| Tracking since | Apr 22, 2015 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+120.9%
5Y
+120.9%
All
+177.3%
Last surveyed Dec 10, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 53% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SODIUM BICARB 8.4% SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for SODIUM BICARB 8.4% SYRINGE, manufactured by International Medication Systems, Limited, is $0.3288 per ML (NDC 76329335201), effective Dec 10, 2025.
How has the price of SODIUM BICARB 8.4% SYRINGE changed over time?
Over the history we have for it, the NADAC for SODIUM BICARB 8.4% SYRINGE has risen 177.3%. It has been tracked across 165 weekly CMS publications since Apr 22, 2015.
What are the highest and lowest recorded NADAC prices for SODIUM BICARB 8.4% SYRINGE?
Since Apr 22, 2015, the NADAC for SODIUM BICARB 8.4% SYRINGE has ranged from a low of $0.1186 (Apr 22, 2015) to a high of $0.3288 (Dec 10, 2025), with a median of $0.1489 per ML.
Are there cheaper alternatives to SODIUM BICARB 8.4% SYRINGE?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SODIUM BICARBONATE 8.4% VIAL, is $0.1540 per ML — about 53% below SODIUM BICARB 8.4% SYRINGE.
Who manufactures SODIUM BICARB 8.4% SYRINGE?
SODIUM BICARB 8.4% SYRINGE (NDC 76329335201) is labeled by International Medication Systems, Limited, and CMS classifies it as a generic product.
Is SODIUM BICARB 8.4% SYRINGE in shortage?
Yes — NDC 76329335201 is currently listed in FDA's drug shortage database (posted Mar 1, 2017). Reported reason: Demand increase for the drug.