Product Information

HYZAAR 50-12.5 TABLET is a brand product labeled by Organon LLC, priced at $5.0084 per EA under NDC 78206013901. Its NADAC has been published 223 times since May 18, 2022.

FDA first approved this application on Apr 28, 1995. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the losartan potassium and hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

HYZAAR 50-12.5 TABLET

losartan potassium and hydrochlorothiazide
$5.0084per EA
High Outlier

Strength

12.5; 50 mg/1; mg/1

Manufacturer

Organon LLC

NDC

78206013901

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

1/1/2026

Approval Type

New Drug (NDA)

FDA Application

NDA020387

FDA Approved

4/28/1995

TE Code

AB

On Market Since

6/1/2021

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for HYZAAR 50-12.5 TABLET has been published 223 times since May 18, 2022, and over the history we have for it it has risen 21.1%. The table below summarizes its recorded NADAC range and movement.

Current price$5.0084 per EA
All-time high$5.0084 (Aug 19, 2026)
All-time low$4.1349 (May 18, 2022)
52-week high$5.0084
52-week low$4.7461
Median price$4.5347
Average price$4.5762
Largest weekly change+6.0% (Jan 18, 2023)
Weeks tracked223
Tracking sinceMay 18, 2022

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+5.5%

3Y

+10.5%

5Y

N/A

All

+21.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYZAAR 50-12.5 TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYZAAR 50-12.5 TABLET, manufactured by Organon LLC, is $5.0084 per EA (NDC 78206013901), effective Aug 19, 2026.

How has the price of HYZAAR 50-12.5 TABLET changed over time?

Over the history we have for it, the NADAC for HYZAAR 50-12.5 TABLET has risen 21.1%. It has been tracked across 223 weekly CMS publications since May 18, 2022.

What are the highest and lowest recorded NADAC prices for HYZAAR 50-12.5 TABLET?

Since May 18, 2022, the NADAC for HYZAAR 50-12.5 TABLET has ranged from a low of $4.1349 (May 18, 2022) to a high of $5.0084 (Aug 19, 2026), with a median of $4.5347 per EA.

Are there cheaper alternatives to HYZAAR 50-12.5 TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, is $0.0573 per EA — about 99% below HYZAAR 50-12.5 TABLET.

Who manufactures HYZAAR 50-12.5 TABLET?

HYZAAR 50-12.5 TABLET (NDC 78206013901) is labeled by Organon LLC, and CMS classifies it as a brand product.