Acetylcysteine
20 NDCs across 6 manufacturers|20 Generic,0 Brand
Acetylcysteine is used to treat amyloidosis, bronchiectasis, bronchitis, cystic fibrosis, drug-related side effects and adverse reactions and pneumonia, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Oct 14, 1986. In 2024, Medicare Part D spent $2 million on Acetylcysteine across 21,000 claims for 5,326 beneficiaries.
Acetylcysteine is available as 20 NDCs from 6 manufacturers (20 generic, 0 brand), with NADAC prices from $0.64 to $6.14 per ML — the most expensive product costs about 9.7× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
20
20G / 0B
Manufacturers
6
competing in market
Price Spread
$0.64 – $6.14
per ML
7d Activity
avg +0.5% WoW · of 20 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Fresenius Kabi USA, LLC manufacturer profile
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Lead class
Antidote class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
6 manufacturers producing ACETYLCYSTEINE(2 pricing outliers)
Frequently Asked Questions
What is Acetylcysteine used to treat?
Acetylcysteine is used to treat amyloidosis, bronchiectasis, bronchitis, cystic fibrosis, drug-related side effects and adverse reactions and pneumonia, per the National Library of Medicine's MED-RT classification.
When did Acetylcysteine become available as a generic?
FDA approved the first generic Acetylcysteine (ANDA) on Oct 14, 1986.
How much does Medicare spend on Acetylcysteine?
In 2024, Medicare Part D spent $2 million on Acetylcysteine across 21,000 claims for 5,326 beneficiaries.
How many Acetylcysteine products are on the market?
The Acetylcysteine drug market contains 20 NDCs from 6 manufacturers — 20 generic and 0 brand products.
What is the price range for Acetylcysteine?
NADAC reference prices for Acetylcysteine range from $0.6356 to $6.1376 per ML — the most expensive product costs about 9.7× the cheapest.
Which manufacturers make Acetylcysteine?
6 manufacturers list Acetylcysteine in NADAC. Ranked by number of NDCs, the largest are Fresenius Kabi USA, LLC (9), Somerset Therapeutics, LLC (3), American Regent, Inc. (3), Cameron Pharmaceuticals (2), Hospira Inc. (2).
How has the price of Acetylcysteine changed recently?
Over the past 7 days, 21 Acetylcysteine NDCs rose and 24 fell, with a market-wide average change of +0.5%.