Acetylcysteine

20 NDCs across 6 manufacturers|20 Generic,0 Brand

Acetylcysteine is used to treat amyloidosis, bronchiectasis, bronchitis, cystic fibrosis, drug-related side effects and adverse reactions and pneumonia, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Oct 14, 1986. In 2024, Medicare Part D spent $2 million on Acetylcysteine across 21,000 claims for 5,326 beneficiaries.

Acetylcysteine is available as 20 NDCs from 6 manufacturers (20 generic, 0 brand), with NADAC prices from $0.64 to $6.14 per ML — the most expensive product costs about 9.7× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

20G / 0B

Manufacturers

competing in market

Price Spread

$0.64 – $6.14

per ML

7d Activity

45↓-25 flat

avg -1.4% WoW · of 20 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

6 manufacturers producing ACETYLCYSTEINE(2 pricing outliers)

Fresenius Kabi USA, LLC

9 NDCs

$1.9428

avg/unit

Somerset Therapeutics, LLC

3 NDCs

$1.8412

avg/unit

American Regent, Inc.

3 NDCs

$1.9902

avg/unit

Cameron Pharmaceuticals

Drug Portfolio

20 NDCs total, 20 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
ACETYLCYSTEINE 6 GRAM/30 ML VL	63323096330	Fresenius Kabi USA, LLC	$6.1376 per ML	—	Generic	—	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 6 GRAM/30 ML VL	00574080530	Padagis US LLC	$6.1376 per ML	High Outlier	Generic	—	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	70069001825	Somerset Therapeutics, LLC	$2.6189 per ML	—	Generic	-0.92%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	63323069504	Fresenius Kabi USA, LLC	$2.6189 per ML	—	Generic	-0.92%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	42494043525	Cameron Pharmaceuticals	$2.6189 per ML	—	Generic	-0.92%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	00517750425	American Regent, Inc.	$2.6189 per ML	—	Generic	-0.92%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	63323069444	Fresenius Kabi USA, LLC	$2.1633 per ML	—	Generic	-3.00%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	00517760425	American Regent, Inc.	$2.1633 per ML	—	Generic	-3.00%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	42494043625	Cameron Pharmaceuticals	$2.1633 per ML	—	Generic	-3.00%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	63323069404	Fresenius Kabi USA, LLC	$2.1633 per ML	—	Generic	-3.00%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	70069001925	Somerset Therapeutics, LLC	$2.1633 per ML	—	Generic	-3.00%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	63323069210	Fresenius Kabi USA, LLC	$1.3184 per ML	—	Generic	—	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL	00517761003	American Regent, Inc.	$1.1883 per ML	—	Generic	—	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	63323069310	Fresenius Kabi USA, LLC	$0.9656 per ML	—	Generic	—	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	63323069030	Fresenius Kabi USA, LLC	$0.7413 per ML	—	Generic	-0.45%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	70069002003	Somerset Therapeutics, LLC	$0.7413 per ML	—	Generic	-0.45%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	63323069044	Fresenius Kabi USA, LLC	$0.7413 per ML	—	Generic	-0.45%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)	00409330803	Hospira Inc.	$0.7413 per ML	Low Outlier	Generic	-0.45%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	00409330703	Hospira Inc.	$0.6351 per ML	Low Outlier	Generic	-0.29%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic
ACETYLCYSTEINE 10% VIAL (NOT FOR INJECTION)	63323069130	Fresenius Kabi USA, LLC	$0.6351 per ML	—	Generic	-0.29%	Antidote, Antidote for Acetaminophen Overdose, Mucolytic

Frequently Asked Questions

What is Acetylcysteine used to treat?

When did Acetylcysteine become available as a generic?

FDA approved the first generic Acetylcysteine (ANDA) on Oct 14, 1986.

How much does Medicare spend on Acetylcysteine?

In 2024, Medicare Part D spent $2 million on Acetylcysteine across 21,000 claims for 5,326 beneficiaries.

How many Acetylcysteine products are on the market?

The Acetylcysteine drug market contains 20 NDCs from 6 manufacturers — 20 generic and 0 brand products.

What is the price range for Acetylcysteine?

NADAC reference prices for Acetylcysteine range from $0.6351 to $6.1376 per ML — the most expensive product costs about 9.7× the cheapest.

Which manufacturers make Acetylcysteine?

6 manufacturers list Acetylcysteine in NADAC. Ranked by number of NDCs, the largest are Fresenius Kabi USA, LLC (9), Somerset Therapeutics, LLC (3), American Regent, Inc. (3), Cameron Pharmaceuticals (2), Hospira Inc. (2).

How has the price of Acetylcysteine changed recently?

Over the past 7 days, 0 Acetylcysteine NDCs rose and 45 fell, with a market-wide average change of -1.4%.