Product Information
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) is a generic product labeled by Fresenius Kabi USA, LLC, priced at $2.2455 per ML under NDC 63323069444. Its NADAC has been published 222 times since Aug 4, 2021.
FDA first approved this application on Jun 21, 2012. Its Orange Book therapeutic-equivalence code is AN.
Strength
200 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323069444
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL; RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
ACETYLCYSTEINEApproval Type
Generic (ANDA)
FDA Application
ANDA203853FDA Approved
6/21/2012
TE Code
AN
On Market Since
9/1/2012
Pharmacological Classes
Price Statistics
The NADAC for ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) has been published 222 times since Aug 4, 2021, and over the history we have for it it has risen 36.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.2455 per ML |
|---|---|
| All-time high | $2.6444 (Oct 15, 2025) |
| All-time low | $1.6443 (Aug 4, 2021) |
| 52-week high | $2.6444 |
| 52-week low | $2.1633 |
| Median price | $2.3421 |
| Average price | $2.1902 |
| Largest weekly change | +32.7% (Aug 23, 2023) |
| Weeks tracked | 222 |
| Tracking since | Aug 4, 2021 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 67% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Fresenius Kabi USA, LLC manufacturer profile
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Drug market
ACETYLCYSTEINE market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Antidote class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)?
The current National Average Drug Acquisition Cost (NADAC) for ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION), manufactured by Fresenius Kabi USA, LLC, is $2.2455 per ML (NDC 63323069444), effective Sep 30, 2026.
How has the price of ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) changed over time?
Over the history we have for it, the NADAC for ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) has risen 36.6%. It has been tracked across 222 weekly CMS publications since Aug 4, 2021.
What are the highest and lowest recorded NADAC prices for ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)?
Since Aug 4, 2021, the NADAC for ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) has ranged from a low of $1.6443 (Aug 4, 2021) to a high of $2.6444 (Oct 15, 2025), with a median of $2.3421 per ML.
Are there cheaper alternatives to ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION), is $0.7371 per ML — about 67% below ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION).
Who manufactures ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION)?
ACETYLCYSTEINE 20% VIAL (NOT FOR INJECTION) (NDC 63323069444) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.