Methylphenidate

23 NDCs across 5 manufacturers|16 Generic,7 Brand

Methylphenidate is used to treat attention deficit disorder with hyperactivity, depressive disorder and narcolepsy, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Apr 6, 2006, and the first generic was approved Jun 19, 2020. FDA's Orange Book lists 14 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $691K on Methylphenidate across 2,039 claims for 465 beneficiaries.

Methylphenidate is available as 23 NDCs from 5 manufacturers (16 generic, 7 brand), with NADAC prices from $1.81 to $18.08 per EA — the most expensive product costs about 10.0× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Active FDA drug shortage

38 Methylphenidate presentations are currently listed in FDA's drug shortage database (first posted Jul 26, 2023). Shortages can move NADAC prices in the following weeks.

Total NDCs

16G / 7B

Manufacturers

competing in market

Price Spread

$1.81 – $18.08

per EA

7d Activity

16↓7 flat

avg -3.8% WoW · of 23 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

5 manufacturers producing METHYLPHENIDATE(2 pricing outliers)

Mylan Pharmaceuticals Inc.

4 NDCs

$7.3030

avg/unit

Noven Therapeutics, LLC

4 NDCs

$5.7600

avg/unit

Neos Therapeutics Brands, LLC

Drug Portfolio

23 NDCs total, 23 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
COTEMPLA XR-ODT 8.6 MG TABLET	70165010030	Neos Therapeutics Brands, LLC	$18.0754 per EA	High Outlier	Brand	—	Central Nervous System Stimulant
COTEMPLA XR-ODT 25.9 MG TABLET	70165030030	Neos Therapeutics Brands, LLC	$17.9890 per EA	High Outlier	Brand	—	Central Nervous System Stimulant
COTEMPLA XR-ODT 17.3 MG TABLET	70165020030	Neos Therapeutics Brands, LLC	$17.9355 per EA	High Outlier	Brand	—	Central Nervous System Stimulant
METHYLPHENIDATE 30 MG/9 HR PATCH	00574243065	Padagis US LLC	$7.8904 per EA	—	Generic	-7.43%	Central Nervous System Stimulant
METHYLPHENIDATE 30 MG/9 HR PATCH	00378826393	Mylan Pharmaceuticals Inc.	$7.8904 per EA	—	Generic	-7.43%	Central Nervous System Stimulant
METHYLPHENIDATE 10 MG/9 HR PATCH	00378826093	Mylan Pharmaceuticals Inc.	$7.2039 per EA	—	Generic	-6.60%	Central Nervous System Stimulant
METHYLPHENIDATE 10 MG/9 HR PATCH	00574241065	Padagis US LLC	$7.2039 per EA	—	Generic	-6.60%	Central Nervous System Stimulant
METHYLPHENIDATE 20 MG/9 HR PATCH	00378826293	Mylan Pharmaceuticals Inc.	$7.1080 per EA	—	Generic	-5.89%	Central Nervous System Stimulant
METHYLPHENIDATE 20 MG/9 HR PATCH	00574242065	Padagis US LLC	$7.1080 per EA	—	Generic	-5.89%	Central Nervous System Stimulant
METHYLPHENIDATE 15 MG/9 HR PATCH	00378826193	Mylan Pharmaceuticals Inc.	$7.0099 per EA	—	Generic	-4.54%	Central Nervous System Stimulant
METHYLPHENIDATE 15 MG/9 HR PATCH	00574241565	Padagis US LLC	$7.0099 per EA	—	Generic	-4.54%	Central Nervous System Stimulant
DAYTRANA 10 MG/9 HR PATCH	68968555203	Noven Therapeutics, LLC	$5.7873 per EA	—	Brand	—	Central Nervous System Stimulant
DAYTRANA 30 MG/9 HOUR PATCH	68968555503	Noven Therapeutics, LLC	$5.7675 per EA	—	Brand	—	Central Nervous System Stimulant
DAYTRANA 15 MG/9 HR PATCH	68968555303	Noven Therapeutics, LLC	$5.7439 per EA	—	Brand	—	Central Nervous System Stimulant
DAYTRANA 20 MG/9 HOUR PATCH	68968555403	Noven Therapeutics, LLC	$5.7414 per EA	—	Brand	—	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 10 MG CP	00781238301	Sandoz Inc.	$2.3035 per EA	Low Outlier	Generic	-1.57%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 10 MG CP	00781236101	Sandoz Inc.	$2.3035 per EA	Low Outlier	Generic	-1.57%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 40 MG CP	00781236401	Sandoz Inc.	$2.0776 per EA	Low Outlier	Generic	-2.07%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 40 MG CP	00781238601	Sandoz Inc.	$2.0776 per EA	Low Outlier	Generic	-2.07%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 30 MG CP	00781238501	Sandoz Inc.	$2.0275 per EA	Low Outlier	Generic	-0.71%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 30 MG CP	00781236301	Sandoz Inc.	$2.0275 per EA	Low Outlier	Generic	-0.71%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 20 MG CP	00781236201	Sandoz Inc.	$1.8123 per EA	Low Outlier	Generic	-1.74%	Central Nervous System Stimulant
METHYLPHENIDATE ER(LA) 20 MG CP	00781238401	Sandoz Inc.	$1.8123 per EA	Low Outlier	Generic	-1.74%	Central Nervous System Stimulant

Frequently Asked Questions

What is Methylphenidate used to treat?

Methylphenidate is used to treat attention deficit disorder with hyperactivity, depressive disorder and narcolepsy, per the National Library of Medicine's MED-RT classification.

When did Methylphenidate become available as a generic?

FDA approved the first generic Methylphenidate (ANDA) on Jun 19, 2020. The Orange Book currently lists 14 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Methylphenidate?

In 2024, Medicare Part D spent $691K on Methylphenidate across 2,039 claims for 465 beneficiaries.

Is Methylphenidate in shortage?

Yes — FDA's drug shortage database currently lists 38 Methylphenidate presentations with status "Current", first posted Jul 26, 2023.

How many Methylphenidate products are on the market?

The Methylphenidate drug market contains 23 NDCs from 5 manufacturers — 16 generic and 7 brand products.

What is the price range for Methylphenidate?

NADAC reference prices for Methylphenidate range from $1.8123 to $18.0754 per EA — the most expensive product costs about 10.0× the cheapest.

Is generic Methylphenidate cheaper than brand?

The average generic NADAC for Methylphenidate is $4.6791 per EA, versus $11.0057 for brand-labeled products — brand versions average about 2.4× the generic price.

Which manufacturers make Methylphenidate?

5 manufacturers list Methylphenidate in NADAC. Ranked by number of NDCs, the largest are Sandoz Inc. (8), Padagis US LLC (4), Mylan Pharmaceuticals Inc. (4), Noven Therapeutics, LLC (4), Neos Therapeutics Brands, LLC (3).

How has the price of Methylphenidate changed recently?

Over the past 7 days, 0 Methylphenidate NDCs rose and 16 fell, with a market-wide average change of -3.8%.