Penicillamine
6 NDCs across 6 manufacturers|5 Generic,1 Brand
Penicillamine is used to treat rheumatoid arthritis, cystinuria, hepatolenticular degeneration, lead poisoning, biliary liver cirrhosis and mercury poisoning, per the National Library of Medicine's MED-RT classification.
▸ More about this market▾ Less
The brand product was first FDA-approved before 1982, and the first generic was approved May 7, 2019. FDA's Orange Book lists 11 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $10 million on Penicillamine across 1,374 claims for 201 beneficiaries.
Penicillamine is available as 6 NDCs from 6 manufacturers (5 generic, 1 brand), with NADAC prices from $9.29 to $255.85 per EA — the most expensive product costs about 28× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
6
5G / 1B
Manufacturers
6
competing in market
Price Spread
$9.29 – $255.85
per EA
7d Activity
avg +0.0% WoW · of 6 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
6 manufacturers producing PENICILLAMINE(1 pricing outlier)
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
CUPRIMINE 250 MG CAPSULE | $255.8478 per EA | — |
PENICILLAMINE 250 MG CAPSULE | $9.2914 per EA | — |
PENICILLAMINE 250 MG CAPSULE | $9.2914 per EA | — |
PENICILLAMINE 250 MG CAPSULE | $9.2914 per EA | — |
PENICILLAMINE 250 MG CAPSULE | $9.2914 per EA | — |
PENICILLAMINE 250 MG CAPSULE | $9.2914 per EA | — |
Frequently Asked Questions
What is Penicillamine used to treat?
Penicillamine is used to treat rheumatoid arthritis, cystinuria, hepatolenticular degeneration, lead poisoning, biliary liver cirrhosis and mercury poisoning, per the National Library of Medicine's MED-RT classification.
When did Penicillamine become available as a generic?
FDA approved the first generic Penicillamine (ANDA) on May 7, 2019. The Orange Book currently lists 11 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Penicillamine?
In 2024, Medicare Part D spent $10 million on Penicillamine across 1,374 claims for 201 beneficiaries.
How many Penicillamine products are on the market?
The Penicillamine drug market contains 6 NDCs from 6 manufacturers — 5 generic and 1 brand product.
What is the price range for Penicillamine?
NADAC reference prices for Penicillamine range from $9.2914 to $255.8478 per EA — the most expensive product costs about 28× the cheapest.
Is generic Penicillamine cheaper than brand?
The average generic NADAC for Penicillamine is $9.2914 per EA, versus $255.8478 for brand-labeled products — brand versions average about 28× the generic price.
Which manufacturers make Penicillamine?
6 manufacturers list Penicillamine in NADAC. Ranked by number of NDCs, the largest are Bausch Health US LLC (1), Dr. Reddy's Laboratories Inc. (1), Endo USA Inc. (1), Breckenridge Pharmaceutical Inc. (1), Actavis Pharma, Inc. (1).