Sodium Zirconium Cyclosilicate
4 NDCs across 1 manufacturer|0 Generic,4 Brand
Sodium Zirconium Cyclosilicate is used to treat hyperkalemia, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on May 18, 2018, and the first generic was approved Aug 7, 2026. FDA's Orange Book lists 4 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $239 million on Sodium Zirconium Cyclosilicate across 335,000 claims for 117,000 beneficiaries.
Sodium Zirconium Cyclosilicate is available as 4 NDCs from 1 manufacturer (0 generic, 4 brand), with NADAC prices from $28.33 to $28.36 per EA — a 0% difference between cheapest and most expensive. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
4
0G / 4B
Manufacturers
1
competing in market
Price Spread
$28.33 – $28.36
per EA
7d Activity
avg +0.0% WoW · of 4 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
AstraZeneca Pharmaceuticals LP manufacturer profile
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
1 manufacturer producing SODIUM ZIRCONIUM CYCLOSILICATE
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
LOKELMA 5 GRAM POWDER PACKET | $28.3616 per EA | +0.02% |
LOKELMA 5 GRAM POWDER PACKET | $28.3616 per EA | +0.02% |
LOKELMA 10 GRAM POWDER PACKET | $28.3300 per EA | 0.00% |
LOKELMA 10 GRAM POWDER PACKET | $28.3300 per EA | 0.00% |
Frequently Asked Questions
What is Sodium Zirconium Cyclosilicate used to treat?
Sodium Zirconium Cyclosilicate is used to treat hyperkalemia, per the National Library of Medicine's MED-RT classification.
When did Sodium Zirconium Cyclosilicate become available as a generic?
FDA approved the first generic Sodium Zirconium Cyclosilicate (ANDA) on Aug 7, 2026. The Orange Book currently lists 4 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Sodium Zirconium Cyclosilicate?
In 2024, Medicare Part D spent $239 million on Sodium Zirconium Cyclosilicate across 335,000 claims for 117,000 beneficiaries.
How many Sodium Zirconium Cyclosilicate products are on the market?
The Sodium Zirconium Cyclosilicate drug market contains 4 NDCs from 1 manufacturer — 0 generic and 4 brand products.
What is the price range for Sodium Zirconium Cyclosilicate?
NADAC reference prices for Sodium Zirconium Cyclosilicate range from $28.3300 to $28.3616 per EA — a 0% difference between cheapest and most expensive.
Which manufacturers make Sodium Zirconium Cyclosilicate?
1 manufacturer lists Sodium Zirconium Cyclosilicate in NADAC. Ranked by number of NDCs, the largest are AstraZeneca Pharmaceuticals LP (4).
How has the price of Sodium Zirconium Cyclosilicate changed recently?
Over the past 7 days, 2 Sodium Zirconium Cyclosilicate NDCs rose and 0 fell, with a market-wide average change of +0.0%.