Product Information
TRULICITY 4.5 MG/0.5 ML PEN is a brand product labeled by Eli Lilly and Company, priced at $487.4181 per ML under NDC 00002318280. Its NADAC has been published 294 times since Feb 17, 2021.
Strength
4.5 mg/.5mL
Manufacturer
Eli Lilly and CompanyNDC
00002318280
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
DULAGLUTIDEApproval Type
Biologic (BLA)
FDA Application
BLA125469On Market Since
9/3/2020
Pharmacological Classes
Price Statistics
The NADAC for TRULICITY 4.5 MG/0.5 ML PEN has been published 294 times since Feb 17, 2021, and over the history we have for it it has risen 20.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $487.4181 per ML |
|---|---|
| All-time high | $487.6323 (May 13, 2026) |
| All-time low | $405.6435 (Feb 17, 2021) |
| 52-week high | $487.6323 |
| 52-week low | $478.0076 |
| Median price | $448.0780 |
| Average price | $451.9049 |
| Largest weekly change | +5.0% (Jan 3, 2024) |
| Weeks tracked | 294 |
| Tracking since | Feb 17, 2021 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Dulaglutide market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Eli Lilly and Company manufacturer profile
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Drug market
Dulaglutide market comparison
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Therapeutic class
GLP-1 Receptor Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRULICITY 4.5 MG/0.5 ML PEN?
The current National Average Drug Acquisition Cost (NADAC) for TRULICITY 4.5 MG/0.5 ML PEN, manufactured by Eli Lilly and Company, is $487.4181 per ML (NDC 00002318280), effective Sep 30, 2026.
How has the price of TRULICITY 4.5 MG/0.5 ML PEN changed over time?
Over the history we have for it, the NADAC for TRULICITY 4.5 MG/0.5 ML PEN has risen 20.2%. It has been tracked across 294 weekly CMS publications since Feb 17, 2021.
What are the highest and lowest recorded NADAC prices for TRULICITY 4.5 MG/0.5 ML PEN?
Since Feb 17, 2021, the NADAC for TRULICITY 4.5 MG/0.5 ML PEN has ranged from a low of $405.6435 (Feb 17, 2021) to a high of $487.6323 (May 13, 2026), with a median of $448.0780 per ML.
Are there cheaper alternatives to TRULICITY 4.5 MG/0.5 ML PEN?
No other NADAC-published product currently shares the active ingredient and strength of TRULICITY 4.5 MG/0.5 ML PEN in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TRULICITY 4.5 MG/0.5 ML PEN?
TRULICITY 4.5 MG/0.5 ML PEN (NDC 00002318280) is labeled by Eli Lilly and Company, and CMS classifies it as a brand product.