Product Information
ZYPREXA ZYDIS 5 MG TABLET is a brand product labeled by Eli Lilly and Company, priced at $16.1177 per EA under NDC 00002445385. Its NADAC has been published 171 times since Dec 18, 2013.
FDA first approved this application on Apr 6, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Eli Lilly and CompanyNDC
00002445385
Classification
Brand
Dosage Form
TABLET, ORALLY DISINTEGRATING
Route
ORAL
Effective Date
9/18/2024
Active Ingredients
OLANZAPINEApproval Type
New Drug (NDA)
FDA Application
NDA021086FDA Approved
4/6/2000
TE Code
AB
On Market Since
6/1/2000
Pharmacological Classes
Price Statistics
The NADAC for ZYPREXA ZYDIS 5 MG TABLET has been published 171 times since Dec 18, 2013, and over the history we have for it it has risen 27.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.1177 per EA |
|---|---|
| All-time high | $16.1177 (Sep 10, 2025) |
| All-time low | $12.6871 (Dec 18, 2013) |
| 52-week high | $16.1177 |
| 52-week low | $16.1177 |
| Median price | $12.8008 |
| Average price | $13.9461 |
| Largest weekly change | +25.9% (Jul 17, 2024) |
| Weeks tracked | 171 |
| Tracking since | Dec 18, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+25.9%
5Y
+25.9%
All
+27.0%
Last surveyed Sep 10, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ZYPREXA ZYDIS 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ZYPREXA ZYDIS 5 MG TABLET, manufactured by Eli Lilly and Company, is $16.1177 per EA (NDC 00002445385), effective Sep 10, 2025.
How has the price of ZYPREXA ZYDIS 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ZYPREXA ZYDIS 5 MG TABLET has risen 27.0%. It has been tracked across 171 weekly CMS publications since Dec 18, 2013.
What are the highest and lowest recorded NADAC prices for ZYPREXA ZYDIS 5 MG TABLET?
Since Dec 18, 2013, the NADAC for ZYPREXA ZYDIS 5 MG TABLET has ranged from a low of $12.6871 (Dec 18, 2013) to a high of $16.1177 (Sep 10, 2025), with a median of $12.8008 per EA.
Are there cheaper alternatives to ZYPREXA ZYDIS 5 MG TABLET?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OLANZAPINE 5 MG TABLET, is $0.0867 per EA — about 99% below ZYPREXA ZYDIS 5 MG TABLET.
Who manufactures ZYPREXA ZYDIS 5 MG TABLET?
ZYPREXA ZYDIS 5 MG TABLET (NDC 00002445385) is labeled by Eli Lilly and Company, and CMS classifies it as a brand product.