Historical record - last NADAC effective date: 9/18/2024
Product Information
ZYPREXA ZYDIS 5 MG TABLET is a brand product labeled by Eli Lilly and Company, priced at $16.1177 per EA under NDC 00002445385. Its NADAC has been published 171 times since Dec 18, 2013.
FDA first approved this application on Apr 6, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Eli Lilly and CompanyNDC
00002445385
Classification
Brand
Dosage Form
TABLET, ORALLY DISINTEGRATING
Route
ORAL
Effective Date
9/18/2024
Active Ingredients
OLANZAPINEApproval Type
New Drug (NDA)
FDA Application
NDA021086FDA Approved
4/6/2000
TE Code
AB
On Market Since
6/1/2000
Pharmacological Classes
Price Statistics
The NADAC for ZYPREXA ZYDIS 5 MG TABLET has been published 171 times since Dec 18, 2013, and over the history we have for it it has risen 27.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.1177 per EA |
|---|---|
| All-time high | $16.1177 (Sep 10, 2025) |
| All-time low | $12.6871 (Dec 18, 2013) |
| Median price | $12.8008 |
| Average price | $13.9461 |
| Largest weekly change | +25.9% (Jul 17, 2024) |
| Weeks tracked | 171 |
| Tracking since | Dec 18, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
+25.9%
5Y
+25.9%
All
+27.0%
Last surveyed Sep 10, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Eli Lilly and Company manufacturer profile
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Drug market
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Therapeutic class
Atypical Antipsychotic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ZYPREXA ZYDIS 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ZYPREXA ZYDIS 5 MG TABLET, manufactured by Eli Lilly and Company, is $16.1177 per EA (NDC 00002445385), effective Sep 10, 2025.
How has the price of ZYPREXA ZYDIS 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ZYPREXA ZYDIS 5 MG TABLET has risen 27.0%. It has been tracked across 171 weekly CMS publications since Dec 18, 2013.
What are the highest and lowest recorded NADAC prices for ZYPREXA ZYDIS 5 MG TABLET?
Since Dec 18, 2013, the NADAC for ZYPREXA ZYDIS 5 MG TABLET has ranged from a low of $12.6871 (Dec 18, 2013) to a high of $16.1177 (Sep 10, 2025), with a median of $12.8008 per EA.
Are there cheaper alternatives to ZYPREXA ZYDIS 5 MG TABLET?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OLANZAPINE 5 MG TABLET, is $0.0867 per EA — about 99% below ZYPREXA ZYDIS 5 MG TABLET.
Who manufactures ZYPREXA ZYDIS 5 MG TABLET?
ZYPREXA ZYDIS 5 MG TABLET (NDC 00002445385) is labeled by Eli Lilly and Company, and CMS classifies it as a brand product.