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Product Information

HUMULIN R 500 UNIT/ML VIAL is a brand product labeled by Eli Lilly and Company, priced at $71.1742 per ML under NDC 00002850101. Its NADAC has been published 651 times since Nov 28, 2013.

HUMULIN R 500 UNIT/ML VIAL

Insulin human
$71.1742per ML

Strength

500 [iU]/mL

NDC

00002850101

Classification

Brand

Dosage Form

INJECTION, SOLUTION

Route

SUBCUTANEOUS

Effective Date

10/22/2025

Active Ingredients

INSULIN HUMAN

Approval Type

Biologic (BLA)

FDA Application

BLA018780

On Market Since

3/31/1994

Pharmacological Classes

Insulin
Insulin

Price Statistics

The NADAC for HUMULIN R 500 UNIT/ML VIAL has been published 651 times since Nov 28, 2013, and over the history we have for it it has risen 76.6%. The table below summarizes its recorded NADAC range and movement.

Current price$71.1742 per ML
All-time high$71.8585 (Jun 14, 2017)
All-time low$40.2974 (Nov 28, 2013)
52-week high$71.2034
52-week low$71.1742
Median price$71.1871
Average price$67.2158
Largest weekly change+10.1% (Dec 18, 2013)
Weeks tracked651
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

0.0%

1Y

-0.0%

3Y

+0.2%

5Y

-0.0%

All

+76.6%

Last surveyed May 13, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

HUMULIN R 500 UNIT/ML KWIKPEN
Brand
00002882427•Eli Lilly and Company
$91.6381
+29% more

Related Drugs

Same classification

NOVOLIN N 100 UNIT/ML VIAL
Brand
00169183411•Novo Nordisk
$4.6211
per ML
NOVOLIN R 100 UNIT/ML VIAL
Brand
00169183311•Novo Nordisk
$4.6249
per ML
NOVOLIN 70-30 100 UNIT/ML VIAL
Brand
00169183711•Novo Nordisk
$4.6280
per ML
AFREZZA (REGULAR INSULIN) 4 UNIT CARTRIDGE
Brand
47918087490•Mannkind Corporation
$5.1813
per EA
NOVOLIN R 100 UNIT/ML FLEXPEN
Brand
00169300315•Novo Nordisk
$5.8156
per ML
NOVOLIN N 100 UNIT/ML FLEXPEN
Brand
00169300415•Novo Nordisk
$5.8235
per ML
NOVOLIN 70-30 FLEXPEN
Brand
00169300715•Novo Nordisk
$5.8265
per ML
LANTUS 100 UNIT/ML VIAL
Brand
00088222033•Sanofi-Aventis U.S. LLC
$6.1493
per ML
LANTUS SOLOSTAR 100 UNIT/ML
Brand
00088221905•Sanofi-Aventis U.S. LLC
$6.1647
per ML
FIASP 100 UNIT/ML VIAL
Brand
00169320111•Novo Nordisk
$6.9249
per ML

Frequently asked questions

What is the NADAC price of HUMULIN R 500 UNIT/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for HUMULIN R 500 UNIT/ML VIAL, manufactured by Eli Lilly and Company, is $71.1742 per ML (NDC 00002850101), effective May 13, 2026.

How has the price of HUMULIN R 500 UNIT/ML VIAL changed over time?

Over the history we have for it, the NADAC for HUMULIN R 500 UNIT/ML VIAL has risen 76.6%. It has been tracked across 651 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for HUMULIN R 500 UNIT/ML VIAL?

Since Nov 28, 2013, the NADAC for HUMULIN R 500 UNIT/ML VIAL has ranged from a low of $40.2974 (Nov 28, 2013) to a high of $71.8585 (Jun 14, 2017), with a median of $71.1871 per ML.

Are there cheaper alternatives to HUMULIN R 500 UNIT/ML VIAL?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as HUMULIN R 500 UNIT/ML VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures HUMULIN R 500 UNIT/ML VIAL?

HUMULIN R 500 UNIT/ML VIAL (NDC 00002850101) is labeled by Eli Lilly and Company, and CMS classifies it as a brand product.