Product Information
ISENTRESS 400 MG TABLET is a brand product labeled by Merck Sharp & Dohme LLC, priced at $34.5434 per EA under NDC 00006022761. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Oct 12, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 mg/1
Manufacturer
Merck Sharp & Dohme LLCNDC
00006022761
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
RALTEGRAVIR POTASSIUMApproval Type
New Drug (NDA)
FDA Application
NDA022145FDA Approved
10/12/2007
TE Code
AB
On Market Since
10/12/2007
Pharmacological Classes
Price Statistics
The NADAC for ISENTRESS 400 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 100.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $34.5434 per EA |
|---|---|
| All-time high | $34.5623 (May 13, 2026) |
| All-time low | $17.2597 (Nov 28, 2013) |
| 52-week high | $34.5623 |
| 52-week low | $33.7791 |
| Median price | $26.7792 |
| Average price | $26.2293 |
| Largest weekly change | +7.9% (Jan 17, 2018) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the RALTEGRAVIR market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISENTRESS 400 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ISENTRESS 400 MG TABLET, manufactured by Merck Sharp & Dohme LLC, is $34.5434 per EA (NDC 00006022761), effective Aug 19, 2026.
How has the price of ISENTRESS 400 MG TABLET changed over time?
Over the history we have for it, the NADAC for ISENTRESS 400 MG TABLET has risen 100.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ISENTRESS 400 MG TABLET?
Since Nov 28, 2013, the NADAC for ISENTRESS 400 MG TABLET has ranged from a low of $17.2597 (Nov 28, 2013) to a high of $34.5623 (May 13, 2026), with a median of $26.7792 per EA.
Are there cheaper alternatives to ISENTRESS 400 MG TABLET?
No other NADAC-published product currently shares the active ingredient and strength of ISENTRESS 400 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ISENTRESS 400 MG TABLET?
ISENTRESS 400 MG TABLET (NDC 00006022761) is labeled by Merck Sharp & Dohme LLC, and CMS classifies it as a brand product.