Product Information
PROTONIX DR 40 MG TABLET is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $14.2145 per EA under NDC 00008084181. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Feb 2, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the PANTOPRAZOLE SODIUM market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
40 mg/1
NDC
00008084181
Classification
Brand
Dosage Form
TABLET, DELAYED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PANTOPRAZOLE SODIUMApproval Type
New Drug (NDA)
FDA Application
NDA020987FDA Approved
2/2/2000
TE Code
AB
On Market Since
5/1/2000
Pharmacological Classes
Price Statistics
The NADAC for PROTONIX DR 40 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 119.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $14.2145 per EA |
|---|---|
| All-time high | $16.7512 (Nov 29, 2023) |
| All-time low | $6.4745 (Nov 28, 2013) |
| 52-week high | $14.2321 |
| 52-week low | $13.7995 |
| Median price | $13.9035 |
| Average price | $13.1020 |
| Largest weekly change | -17.0% (Dec 6, 2023) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROTONIX DR 40 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROTONIX DR 40 MG TABLET, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $14.2145 per EA (NDC 00008084181), effective Aug 19, 2026.
How has the price of PROTONIX DR 40 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROTONIX DR 40 MG TABLET has risen 119.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROTONIX DR 40 MG TABLET?
Since Nov 28, 2013, the NADAC for PROTONIX DR 40 MG TABLET has ranged from a low of $6.4745 (Nov 28, 2013) to a high of $16.7512 (Nov 29, 2023), with a median of $13.9035 per EA.
Are there cheaper alternatives to PROTONIX DR 40 MG TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PANTOPRAZOLE SOD DR 40 MG TAB, is $0.0352 per EA — about 99% below PROTONIX DR 40 MG TABLET.
Who manufactures PROTONIX DR 40 MG TABLET?
PROTONIX DR 40 MG TABLET (NDC 00008084181) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.