Product Information

SOLU-CORTEF 250 MG ACT-O-VIAL is a brand product labeled by Pharmacia & Upjohn Company LLC, priced at $51.4321 per EA under NDC 00009001305. Its NADAC has been published 92 times since Nov 20, 2024.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.

SOLU-CORTEF 250 MG ACT-O-VIAL

hydrocortisone sodium succinate
$51.4321per EA

Strength

250 mg/2mL

NDC

00009001305

Classification

Brand

Dosage Form

INJECTION, POWDER, FOR SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS

Effective Date

7/1/2026

Approval Type

New Drug (NDA)

FDA Application

NDA009866

FDA Approved

Before 1982

TE Code

AP

On Market Since

4/27/1955

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for SOLU-CORTEF 250 MG ACT-O-VIAL has been published 92 times since Nov 20, 2024, and over the history we have for it it has risen 35.6%. The table below summarizes its recorded NADAC range and movement.

Current price$51.4321 per EA
All-time high$51.4321 (Aug 19, 2026)
All-time low$37.9160 (Nov 20, 2024)
52-week high$51.4321
52-week low$42.5939
Median price$42.5939
Average price$44.3932
Largest weekly change+15.0% (Dec 31, 2025)
Weeks tracked92
Tracking sinceNov 20, 2024

Price History

1W

0.0%

1M

0.0%

3M

+5.0%

6M

+5.0%

1Y

+20.8%

3Y

N/A

5Y

N/A

All

+35.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 26% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 26%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of SOLU-CORTEF 250 MG ACT-O-VIAL?

The current National Average Drug Acquisition Cost (NADAC) for SOLU-CORTEF 250 MG ACT-O-VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $51.4321 per EA (NDC 00009001305), effective Aug 19, 2026.

How has the price of SOLU-CORTEF 250 MG ACT-O-VIAL changed over time?

Over the history we have for it, the NADAC for SOLU-CORTEF 250 MG ACT-O-VIAL has risen 35.6%. It has been tracked across 92 weekly CMS publications since Nov 20, 2024.

What are the highest and lowest recorded NADAC prices for SOLU-CORTEF 250 MG ACT-O-VIAL?

Since Nov 20, 2024, the NADAC for SOLU-CORTEF 250 MG ACT-O-VIAL has ranged from a low of $37.9160 (Nov 20, 2024) to a high of $51.4321 (Aug 19, 2026), with a median of $42.5939 per EA.

Are there cheaper alternatives to SOLU-CORTEF 250 MG ACT-O-VIAL?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SOLU-CORTEF 250 MG ACT-O-VIAL, is $37.9160 per EA — about 26% below SOLU-CORTEF 250 MG ACT-O-VIAL.

Who manufactures SOLU-CORTEF 250 MG ACT-O-VIAL?

SOLU-CORTEF 250 MG ACT-O-VIAL (NDC 00009001305) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand product.