Product Information
DEPO-ESTRADIOL 5 MG/ML VIAL is a brand (anda) product labeled by Pharmacia & Upjohn Company LLC, priced at $51.9084 per ML under NDC 00009027101. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application before 1982.
Strength
5 mg/mL
Manufacturer
Pharmacia & Upjohn Company LLCNDC
00009027101
Classification
Brand (ANDA)
Dosage Form
INJECTION
Route
INTRAMUSCULAR
Effective Date
7/1/2026
Active Ingredients
ESTRADIOL CYPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA085470FDA Approved
Before 1982
On Market Since
8/15/1979
Pharmacological Classes
Price Statistics
The NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 528.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $51.9084 per ML |
|---|---|
| All-time high | $51.9084 (Sep 30, 2026) |
| All-time low | $8.2597 (Nov 28, 2013) |
| 52-week high | $51.9084 |
| 52-week low | $46.9955 |
| Median price | $22.0287 |
| Average price | $24.9021 |
| Largest weekly change | +15.0% (Jan 7, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol cypionate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Pharmacia & Upjohn Company LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
estradiol cypionate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DEPO-ESTRADIOL 5 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DEPO-ESTRADIOL 5 MG/ML VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $51.9084 per ML (NDC 00009027101), effective Sep 30, 2026.
How has the price of DEPO-ESTRADIOL 5 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has risen 528.5%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DEPO-ESTRADIOL 5 MG/ML VIAL?
Since Nov 28, 2013, the NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has ranged from a low of $8.2597 (Nov 28, 2013) to a high of $51.9084 (Sep 30, 2026), with a median of $22.0287 per ML.
Are there cheaper alternatives to DEPO-ESTRADIOL 5 MG/ML VIAL?
No other NADAC-published product currently shares the active ingredient and strength of DEPO-ESTRADIOL 5 MG/ML VIAL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures DEPO-ESTRADIOL 5 MG/ML VIAL?
DEPO-ESTRADIOL 5 MG/ML VIAL (NDC 00009027101) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand (anda) product.