Product Information

DEPO-ESTRADIOL 5 MG/ML VIAL is a brand (anda) product labeled by Pharmacia & Upjohn Company LLC, priced at $51.9084 per ML under NDC 00009027101. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application before 1982.

DEPO-ESTRADIOL 5 MG/ML VIAL

estradiol cypionate
$51.9084per ML

Strength

5 mg/mL

NDC

00009027101

Classification

Brand (ANDA)

Dosage Form

INJECTION

Route

INTRAMUSCULAR

Effective Date

7/1/2026

Active Ingredients

ESTRADIOL CYPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA085470

FDA Approved

Before 1982

On Market Since

8/15/1979

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 528.5%. The table below summarizes its recorded NADAC range and movement.

Current price$51.9084 per ML
All-time high$51.9084 (Aug 19, 2026)
All-time low$8.2597 (Nov 28, 2013)
52-week high$51.9084
52-week low$46.9955
Median price$22.0287
Average price$24.6584
Largest weekly change+15.0% (Jan 7, 2015)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

0.0%

3M

+5.1%

6M

+5.2%

1Y

+7.0%

3Y

+60.4%

5Y

+132.8%

All

+528.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol cypionate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of DEPO-ESTRADIOL 5 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DEPO-ESTRADIOL 5 MG/ML VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $51.9084 per ML (NDC 00009027101), effective Aug 19, 2026.

How has the price of DEPO-ESTRADIOL 5 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has risen 528.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for DEPO-ESTRADIOL 5 MG/ML VIAL?

Since Nov 28, 2013, the NADAC for DEPO-ESTRADIOL 5 MG/ML VIAL has ranged from a low of $8.2597 (Nov 28, 2013) to a high of $51.9084 (Aug 19, 2026), with a median of $22.0287 per ML.

Are there cheaper alternatives to DEPO-ESTRADIOL 5 MG/ML VIAL?

No other NADAC-published product currently shares the active ingredient and strength of DEPO-ESTRADIOL 5 MG/ML VIAL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures DEPO-ESTRADIOL 5 MG/ML VIAL?

DEPO-ESTRADIOL 5 MG/ML VIAL (NDC 00009027101) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand (anda) product.