Product Information
ESTRACE 0.01% CREAM is a brand (anda) product labeled by Allergan, Inc., priced at $7.7613 per GM under NDC 00430375414. Its NADAC has been published 623 times since Nov 28, 2013.
FDA first approved this application on Jan 31, 1984. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 mg/g
Manufacturer
Allergan, Inc.NDC
00430375414
Classification
Brand (ANDA)
Dosage Form
CREAM
Route
VAGINAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA086069FDA Approved
1/31/1984
TE Code
AB
On Market Since
7/1/2001
Pharmacological Classes
Price Statistics
The NADAC for ESTRACE 0.01% CREAM has been published 623 times since Nov 28, 2013, and over the history we have for it it has risen 139.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.7613 per GM |
|---|---|
| All-time high | $7.8157 (Jun 15, 2022) |
| All-time low | $3.2411 (Nov 28, 2013) |
| 52-week high | $7.7764 |
| 52-week low | $7.7161 |
| Median price | $7.7393 |
| Average price | $6.8430 |
| Largest weekly change | +19.9% (Jun 10, 2015) |
| Weeks tracked | 623 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 95% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRACE 0.01% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for ESTRACE 0.01% CREAM, manufactured by Allergan, Inc., is $7.7613 per GM (NDC 00430375414), effective Aug 19, 2026.
How has the price of ESTRACE 0.01% CREAM changed over time?
Over the history we have for it, the NADAC for ESTRACE 0.01% CREAM has risen 139.5%. It has been tracked across 623 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ESTRACE 0.01% CREAM?
Since Nov 28, 2013, the NADAC for ESTRACE 0.01% CREAM has ranged from a low of $3.2411 (Nov 28, 2013) to a high of $7.8157 (Jun 15, 2022), with a median of $7.7393 per GM.
Are there cheaper alternatives to ESTRACE 0.01% CREAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.01% CREAM, is $0.4257 per GM — about 95% below ESTRACE 0.01% CREAM.
Who manufactures ESTRACE 0.01% CREAM?
ESTRACE 0.01% CREAM (NDC 00430375414) is labeled by Allergan, Inc., and CMS classifies it as a brand (anda) product.