Product Information
REFRESH PLUS 0.5% EYE DROPS is a brand product labeled by Allergan, Inc., priced at $0.2968 per EA under NDC 00023040330. Its NADAC has been published 456 times since Nov 28, 2013.
Strength
5 mg/mL
Manufacturer
Allergan, Inc.NDC
00023040330
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
CARBOXYMETHYLCELLULOSE SODIUMApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
10/9/1996
Price Statistics
The NADAC for REFRESH PLUS 0.5% EYE DROPS has been published 456 times since Nov 28, 2013, and over the history we have for it it has risen 18.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2968 per EA |
|---|---|
| All-time high | $0.2969 (Aug 12, 2026) |
| All-time low | $0.2510 (Aug 20, 2014) |
| 52-week high | $0.2969 |
| 52-week low | $0.2966 |
| Median price | $0.2767 |
| Average price | $0.2776 |
| Largest weekly change | +12.1% (Mar 12, 2014) |
| Weeks tracked | 456 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of REFRESH PLUS 0.5% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for REFRESH PLUS 0.5% EYE DROPS, manufactured by Allergan, Inc., is $0.2968 per EA (NDC 00023040330), effective Aug 19, 2026.
How has the price of REFRESH PLUS 0.5% EYE DROPS changed over time?
Over the history we have for it, the NADAC for REFRESH PLUS 0.5% EYE DROPS has risen 18.1%. It has been tracked across 456 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for REFRESH PLUS 0.5% EYE DROPS?
Since Nov 28, 2013, the NADAC for REFRESH PLUS 0.5% EYE DROPS has ranged from a low of $0.2510 (Aug 20, 2014) to a high of $0.2969 (Aug 12, 2026), with a median of $0.2767 per EA.
Are there cheaper alternatives to REFRESH PLUS 0.5% EYE DROPS?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CARBOXYMETHYLCELL 0.5% EYE DRP, is $0.1549 per EA — about 48% below REFRESH PLUS 0.5% EYE DROPS.
Who manufactures REFRESH PLUS 0.5% EYE DROPS?
REFRESH PLUS 0.5% EYE DROPS (NDC 00023040330) is labeled by Allergan, Inc., and CMS classifies it as a brand product.