Product Information
REFRESH PLUS 0.5% EYE DROPS is a brand product labeled by Allergan, Inc., priced at $0.2764 per EA under NDC 00023040350. Its NADAC has been published 501 times since Nov 28, 2013.
Strength
5 mg/mL
Manufacturer
Allergan, Inc.NDC
00023040350
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
1/21/2026
Active Ingredients
CARBOXYMETHYLCELLULOSE SODIUMApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
10/9/1996
Price Statistics
The NADAC for REFRESH PLUS 0.5% EYE DROPS has been published 501 times since Nov 28, 2013, and over the history we have for it it has risen 15.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2764 per EA |
|---|---|
| All-time high | $0.2818 (Feb 13, 2019) |
| All-time low | $0.2332 (Jan 22, 2014) |
| 52-week high | $0.2764 |
| 52-week low | $0.2764 |
| Median price | $0.2601 |
| Average price | $0.2612 |
| Largest weekly change | +12.1% (Mar 12, 2014) |
| Weeks tracked | 501 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 46% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of REFRESH PLUS 0.5% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for REFRESH PLUS 0.5% EYE DROPS, manufactured by Allergan, Inc., is $0.2764 per EA (NDC 00023040350), effective Jun 24, 2026.
How has the price of REFRESH PLUS 0.5% EYE DROPS changed over time?
Over the history we have for it, the NADAC for REFRESH PLUS 0.5% EYE DROPS has risen 15.8%. It has been tracked across 501 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for REFRESH PLUS 0.5% EYE DROPS?
Since Nov 28, 2013, the NADAC for REFRESH PLUS 0.5% EYE DROPS has ranged from a low of $0.2332 (Jan 22, 2014) to a high of $0.2818 (Feb 13, 2019), with a median of $0.2601 per EA.
Are there cheaper alternatives to REFRESH PLUS 0.5% EYE DROPS?
Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CARBOXYMETHYLCELL 0.5% EYE DRP, is $0.1496 per EA — about 46% below REFRESH PLUS 0.5% EYE DROPS.
Who manufactures REFRESH PLUS 0.5% EYE DROPS?
REFRESH PLUS 0.5% EYE DROPS (NDC 00023040350) is labeled by Allergan, Inc., and CMS classifies it as a brand product.
Related Drugs
Same classification