Product Information
REFRESH TEARS 0.5% EYE DROP is a brand product labeled by Allergan, Inc., priced at $0.5578 per ML under NDC 00023079815. Its NADAC has been published 450 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the carboxymethylcellulose sodium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
5 mg/mL
Manufacturer
Allergan, Inc.NDC
00023079815
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
CARBOXYMETHYLCELLULOSE SODIUMApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
5/16/1997
Price Statistics
The NADAC for REFRESH TEARS 0.5% EYE DROP has been published 450 times since Nov 28, 2013, and over the history we have for it it has risen 13.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5578 per ML |
|---|---|
| All-time high | $0.5593 (Sep 10, 2025) |
| All-time low | $0.4927 (Dec 18, 2013) |
| 52-week high | $0.5591 |
| 52-week low | $0.5578 |
| Median price | $0.5287 |
| Average price | $0.5290 |
| Largest weekly change | +3.9% (Apr 22, 2015) |
| Weeks tracked | 450 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Allergan, Inc. manufacturer profile
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Drug market
carboxymethylcellulose sodium market comparison
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of REFRESH TEARS 0.5% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for REFRESH TEARS 0.5% EYE DROP, manufactured by Allergan, Inc., is $0.5578 per ML (NDC 00023079815), effective Sep 30, 2026.
How has the price of REFRESH TEARS 0.5% EYE DROP changed over time?
Over the history we have for it, the NADAC for REFRESH TEARS 0.5% EYE DROP has risen 13.1%. It has been tracked across 450 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for REFRESH TEARS 0.5% EYE DROP?
Since Nov 28, 2013, the NADAC for REFRESH TEARS 0.5% EYE DROP has ranged from a low of $0.4927 (Dec 18, 2013) to a high of $0.5593 (Sep 10, 2025), with a median of $0.5287 per ML.
Are there cheaper alternatives to REFRESH TEARS 0.5% EYE DROP?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LUBRICANT 0.5% EYE DROP, is $0.2920 per ML — about 48% below REFRESH TEARS 0.5% EYE DROP.
Who manufactures REFRESH TEARS 0.5% EYE DROP?
REFRESH TEARS 0.5% EYE DROP (NDC 00023079815) is labeled by Allergan, Inc., and CMS classifies it as a brand product.