Product Information

REFRESH OPTIVE ADVANCED DROPS is a brand product labeled by Allergan, Inc., priced at $1.0322 per ML under NDC 00023430710. Its NADAC has been published 548 times since Nov 28, 2013.

REFRESH OPTIVE ADVANCED DROPS

carboxymethylcellulose sodium, glycerin, and polysorbate 80
$1.0322per ML
OTC

Strength

5; 10; 5 mg/mL; mg/mL; mg/mL

Manufacturer

Allergan, Inc.

NDC

00023430710

Classification

Brand

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Last Updated

5/20/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M018

On Market Since

11/30/2011

Pharmacological Classes

Allergens
Cell-mediated Immunity
Glycerol
Increased Histamine Release
Increased IgG Production
Non-Standardized Chemical Allergen

Price Statistics

The NADAC for REFRESH OPTIVE ADVANCED DROPS has been published 548 times since Nov 28, 2013, and over the history we have for it it has risen 7.8%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0322 per ML
All-time high$1.0337 (Sep 10, 2025)
All-time low$0.9460 (Sep 23, 2015)
52-week high$1.0337
52-week low$1.0308
Median price$0.9814
Average price$0.9845
Largest weekly change+5.3% (Jun 19, 2024)
Weeks tracked548
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

0.0%

3M

+0.0%

6M

-0.1%

1Y

-0.1%

3Y

+5.3%

5Y

+5.3%

All

+7.8%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 4%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of REFRESH OPTIVE ADVANCED DROPS?

The current National Average Drug Acquisition Cost (NADAC) for REFRESH OPTIVE ADVANCED DROPS, manufactured by Allergan, Inc., is $1.0322 per ML (NDC 00023430710), effective Jun 24, 2026.

How has the price of REFRESH OPTIVE ADVANCED DROPS changed over time?

Over the history we have for it, the NADAC for REFRESH OPTIVE ADVANCED DROPS has risen 7.8%. It has been tracked across 548 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for REFRESH OPTIVE ADVANCED DROPS?

Since Nov 28, 2013, the NADAC for REFRESH OPTIVE ADVANCED DROPS has ranged from a low of $0.9460 (Sep 23, 2015) to a high of $1.0337 (Sep 10, 2025), with a median of $0.9814 per ML.

Are there cheaper alternatives to REFRESH OPTIVE ADVANCED DROPS?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, REFRESH OPTIVE ADVANCED DROPS, is $0.9871 per ML — about 4% below REFRESH OPTIVE ADVANCED DROPS.

Who manufactures REFRESH OPTIVE ADVANCED DROPS?

REFRESH OPTIVE ADVANCED DROPS (NDC 00023430710) is labeled by Allergan, Inc., and CMS classifies it as a brand product.