Product Information
REFRESH OPTIVE ADVANCED DROPS is a brand product labeled by Allergan, Inc., priced at $0.4448 per EA under NDC 00023449130. Its NADAC has been published 663 times since Jan 22, 2014.
Strength
5; 10; 5 mg/mL; mg/mL; mg/mL
Manufacturer
Allergan, Inc.NDC
00023449130
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
CARBOXYMETHYLCELLULOSE SODIUM; GLYCERIN; POLYSORBATE 80Approval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
1/15/2013
Pharmacological Classes
Price Statistics
The NADAC for REFRESH OPTIVE ADVANCED DROPS has been published 663 times since Jan 22, 2014, and over the history we have for it it has risen 26.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4448 per EA |
|---|---|
| All-time high | $0.4519 (Jan 15, 2025) |
| All-time low | $0.3388 (Apr 23, 2014) |
| 52-week high | $0.4471 |
| 52-week low | $0.4436 |
| Median price | $0.4015 |
| Average price | $0.4004 |
| Largest weekly change | -8.8% (Oct 18, 2017) |
| Weeks tracked | 663 |
| Tracking since | Jan 22, 2014 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the carboxymethylcellulose sodium, glycerin, polysorbate 80 market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Allergan, Inc. manufacturer profile
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Drug market
carboxymethylcellulose sodium, glycerin, polysorbate 80 market comparison
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Therapeutic class
Non-Standardized Chemical Allergen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of REFRESH OPTIVE ADVANCED DROPS?
The current National Average Drug Acquisition Cost (NADAC) for REFRESH OPTIVE ADVANCED DROPS, manufactured by Allergan, Inc., is $0.4448 per EA (NDC 00023449130), effective Sep 30, 2026.
How has the price of REFRESH OPTIVE ADVANCED DROPS changed over time?
Over the history we have for it, the NADAC for REFRESH OPTIVE ADVANCED DROPS has risen 26.9%. It has been tracked across 663 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for REFRESH OPTIVE ADVANCED DROPS?
Since Jan 22, 2014, the NADAC for REFRESH OPTIVE ADVANCED DROPS has ranged from a low of $0.3388 (Apr 23, 2014) to a high of $0.4519 (Jan 15, 2025), with a median of $0.4015 per EA.
Are there cheaper alternatives to REFRESH OPTIVE ADVANCED DROPS?
No other NADAC-published product currently shares the active ingredient and strength of REFRESH OPTIVE ADVANCED DROPS in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures REFRESH OPTIVE ADVANCED DROPS?
REFRESH OPTIVE ADVANCED DROPS (NDC 00023449130) is labeled by Allergan, Inc., and CMS classifies it as a brand product.