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Product Information

REFRESH OPTIVE ADVANCED DROPS is a brand product labeled by Allergan, Inc., priced at $0.4448 per EA under NDC 00023449130. Its NADAC has been published 657 times since Jan 22, 2014.

REFRESH OPTIVE ADVANCED DROPS

carboxymethylcellulose sodium, glycerin, polysorbate 80
$0.4448per EA
OTC

Strength

5; 10; 5 mg/mL; mg/mL; mg/mL

Manufacturer

Allergan, Inc.

NDC

00023449130

Classification

Brand

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M018

On Market Since

1/15/2013

Pharmacological Classes

Allergens
Cell-mediated Immunity
Glycerol
Increased Histamine Release
Increased IgG Production
Non-Standardized Chemical Allergen

Price Statistics

The NADAC for REFRESH OPTIVE ADVANCED DROPS has been published 657 times since Jan 22, 2014, and over the history we have for it it has risen 26.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4448 per EA
All-time high$0.4519 (Jan 15, 2025)
All-time low$0.3388 (Apr 23, 2014)
52-week high$0.4471
52-week low$0.4436
Median price$0.4011
Average price$0.4000
Largest weekly change-8.8% (Oct 18, 2017)
Weeks tracked657
Tracking sinceJan 22, 2014

Price History

1W

+0.3%

1M

+0.3%

3M

+0.3%

6M

-0.0%

1Y

-0.5%

3Y

+6.8%

5Y

+8.7%

All

+26.9%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the carboxymethylcellulose sodium, glycerin, polysorbate 80 market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of REFRESH OPTIVE ADVANCED DROPS?

The current National Average Drug Acquisition Cost (NADAC) for REFRESH OPTIVE ADVANCED DROPS, manufactured by Allergan, Inc., is $0.4448 per EA (NDC 00023449130), effective Aug 19, 2026.

How has the price of REFRESH OPTIVE ADVANCED DROPS changed over time?

Over the history we have for it, the NADAC for REFRESH OPTIVE ADVANCED DROPS has risen 26.9%. It has been tracked across 657 weekly CMS publications since Jan 22, 2014.

What are the highest and lowest recorded NADAC prices for REFRESH OPTIVE ADVANCED DROPS?

Since Jan 22, 2014, the NADAC for REFRESH OPTIVE ADVANCED DROPS has ranged from a low of $0.3388 (Apr 23, 2014) to a high of $0.4519 (Jan 15, 2025), with a median of $0.4011 per EA.

Are there cheaper alternatives to REFRESH OPTIVE ADVANCED DROPS?

No other NADAC-published product currently shares the active ingredient and strength of REFRESH OPTIVE ADVANCED DROPS in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures REFRESH OPTIVE ADVANCED DROPS?

REFRESH OPTIVE ADVANCED DROPS (NDC 00023449130) is labeled by Allergan, Inc., and CMS classifies it as a brand product.