Product Information

REFRESH OPTIVE MEGA-3 PF DROPS is a brand product labeled by Allergan, Inc., priced at $0.4448 per EA under NDC 00023577330. Its NADAC has been published 476 times since Jul 12, 2017.

REFRESH OPTIVE MEGA-3 PF DROPS

Carboxymethylcellulose sodium, Glycerin and Polysorbate 80
$0.4448per EA
OTC

Strength

5; 10; 5 mg/mL; mg/mL; mg/mL

Manufacturer

Allergan, Inc.

NDC

00023577330

Classification

Brand

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M018

On Market Since

5/30/2017

Pharmacological Classes

Allergens
Cell-mediated Immunity
Glycerol
Increased Histamine Release
Increased IgG Production
Non-Standardized Chemical Allergen

Price Statistics

The NADAC for REFRESH OPTIVE MEGA-3 PF DROPS has been published 476 times since Jul 12, 2017, and over the history we have for it it has risen 21.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4448 per EA
All-time high$0.4519 (Jan 15, 2025)
All-time low$0.3625 (Oct 18, 2017)
52-week high$0.4471
52-week low$0.4436
Median price$0.4165
Average price$0.4172
Largest weekly change-8.8% (Oct 18, 2017)
Weeks tracked476
Tracking sinceJul 12, 2017

Price History

1W

+0.3%

1M

+0.3%

3M

+0.3%

6M

-0.0%

1Y

-0.5%

3Y

+6.8%

5Y

+8.7%

All

+21.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of REFRESH OPTIVE MEGA-3 PF DROPS?

The current National Average Drug Acquisition Cost (NADAC) for REFRESH OPTIVE MEGA-3 PF DROPS, manufactured by Allergan, Inc., is $0.4448 per EA (NDC 00023577330), effective Aug 19, 2026.

How has the price of REFRESH OPTIVE MEGA-3 PF DROPS changed over time?

Over the history we have for it, the NADAC for REFRESH OPTIVE MEGA-3 PF DROPS has risen 21.5%. It has been tracked across 476 weekly CMS publications since Jul 12, 2017.

What are the highest and lowest recorded NADAC prices for REFRESH OPTIVE MEGA-3 PF DROPS?

Since Jul 12, 2017, the NADAC for REFRESH OPTIVE MEGA-3 PF DROPS has ranged from a low of $0.3625 (Oct 18, 2017) to a high of $0.4519 (Jan 15, 2025), with a median of $0.4165 per EA.

Are there cheaper alternatives to REFRESH OPTIVE MEGA-3 PF DROPS?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as REFRESH OPTIVE MEGA-3 PF DROPS in a comparable dosage form, but none are currently priced below it.

Who manufactures REFRESH OPTIVE MEGA-3 PF DROPS?

REFRESH OPTIVE MEGA-3 PF DROPS (NDC 00023577330) is labeled by Allergan, Inc., and CMS classifies it as a brand product.