Product Information
LOMOTIL 2.5-0.025 MG TABLET is a brand product labeled by Pfizer Inc., priced at $3.0028 per EA under NDC 00025006131. Its NADAC has been published 360 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the diphenoxylate hydrochloride and atropine sulfate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
.025; 2.5 mg/1; mg/1
Manufacturer
Pfizer Inc.NDC
00025006131
Classification
Brand
Dosage Form
TABLET
Route
ORAL
Last Updated
1/1/2026
Active Ingredients
ATROPINE SULFATE; DIPHENOXYLATE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA012462On Market Since
9/15/1960
Pharmacological Classes
Price Statistics
The NADAC for LOMOTIL 2.5-0.025 MG TABLET has been published 360 times since Nov 28, 2013, and over the history we have for it it has risen 128.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.0028 per EA |
|---|---|
| All-time high | $3.0028 (Mar 11, 2026) |
| All-time low | $1.3173 (Nov 28, 2013) |
| 52-week high | $3.0028 |
| 52-week low | $2.9239 |
| Median price | $2.3057 |
| Average price | $2.2846 |
| Largest weekly change | +9.4% (Jan 10, 2018) |
| Weeks tracked | 360 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 95% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of LOMOTIL 2.5-0.025 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LOMOTIL 2.5-0.025 MG TABLET, manufactured by Pfizer Inc., is $3.0028 per EA (NDC 00025006131), effective Mar 11, 2026.
How has the price of LOMOTIL 2.5-0.025 MG TABLET changed over time?
Over the history we have for it, the NADAC for LOMOTIL 2.5-0.025 MG TABLET has risen 128.0%. It has been tracked across 360 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LOMOTIL 2.5-0.025 MG TABLET?
Since Nov 28, 2013, the NADAC for LOMOTIL 2.5-0.025 MG TABLET has ranged from a low of $1.3173 (Nov 28, 2013) to a high of $3.0028 (Mar 11, 2026), with a median of $2.3057 per EA.
Are there cheaper alternatives to LOMOTIL 2.5-0.025 MG TABLET?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, is $0.1384 per EA — about 95% below LOMOTIL 2.5-0.025 MG TABLET.
Who manufactures LOMOTIL 2.5-0.025 MG TABLET?
LOMOTIL 2.5-0.025 MG TABLET (NDC 00025006131) is labeled by Pfizer Inc., and CMS classifies it as a brand product.
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