Product Information

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1386 per EA under NDC 00406123601. Its NADAC has been published 278 times since Apr 28, 2021.

FDA first approved this application on Oct 6, 2020. Its Orange Book therapeutic-equivalence code is AA.

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET

diphenoxylate hydrochloride and atropine sulfate
$0.1386per EA
DEA Schedule CV

Strength

.025; 2.5 mg/1; mg/1

Manufacturer

SpecGx LLC

NDC

00406123601

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA213335

FDA Approved

10/6/2020

TE Code

AA

On Market Since

10/30/2020

Pharmacological Classes

Anticholinergic
Antidiarrheal
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists

Price Statistics

The NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has been published 278 times since Apr 28, 2021, and over the history we have for it it has declined 34.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1386 per EA
All-time high$0.2446 (Apr 10, 2024)
All-time low$0.1298 (Nov 20, 2024)
52-week high$0.1837
52-week low$0.1371
Median price$0.1840
Average price$0.1846
Largest weekly change+55.5% (Aug 21, 2024)
Weeks tracked278
Tracking sinceApr 28, 2021

Price History

1W

+1.1%

1M

+1.1%

3M

-0.0%

6M

-11.2%

1Y

-24.6%

3Y

-23.0%

5Y

-33.2%

All

-34.6%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, manufactured by SpecGx LLC, is $0.1386 per EA (NDC 00406123601), effective Aug 19, 2026.

How has the price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET changed over time?

Over the history we have for it, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has declined 34.6%. It has been tracked across 278 weekly CMS publications since Apr 28, 2021.

What are the highest and lowest recorded NADAC prices for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

Since Apr 28, 2021, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has ranged from a low of $0.1298 (Nov 20, 2024) to a high of $0.2446 (Apr 10, 2024), with a median of $0.1840 per EA.

Are there cheaper alternatives to DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET (NDC 00406123601) is labeled by SpecGx LLC, and CMS classifies it as a generic product.