Product Information
ARTHROTEC 50 MG-200 MCG TAB is a brand product labeled by Pfizer Inc., priced at $8.5495 per EA under NDC 00025141160. Its NADAC has been published 287 times since Nov 28, 2013.
FDA first approved this application on Dec 24, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the diclofenac sodium and misoprostol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50; 200 mg/1; ug/1
Manufacturer
Pfizer Inc.NDC
00025141160
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
4/22/2026
Active Ingredients
DICLOFENAC SODIUM; MISOPROSTOLApproval Type
New Drug (NDA)
FDA Application
NDA020607FDA Approved
12/24/1997
TE Code
AB
On Market Since
12/24/1997
Pharmacological Classes
Price Statistics
The NADAC for ARTHROTEC 50 MG-200 MCG TAB has been published 287 times since Nov 28, 2013, and over the history we have for it it has risen 143.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.5495 per EA |
|---|---|
| All-time high | $8.5495 (Aug 19, 2026) |
| All-time low | $3.5177 (Nov 28, 2013) |
| 52-week high | $8.5495 |
| 52-week low | $8.5495 |
| Median price | $6.1298 |
| Average price | $6.1435 |
| Largest weekly change | +9.4% (Jan 6, 2016) |
| Weeks tracked | 287 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 92% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ARTHROTEC 50 MG-200 MCG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ARTHROTEC 50 MG-200 MCG TAB, manufactured by Pfizer Inc., is $8.5495 per EA (NDC 00025141160), effective Aug 19, 2026.
How has the price of ARTHROTEC 50 MG-200 MCG TAB changed over time?
Over the history we have for it, the NADAC for ARTHROTEC 50 MG-200 MCG TAB has risen 143.0%. It has been tracked across 287 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ARTHROTEC 50 MG-200 MCG TAB?
Since Nov 28, 2013, the NADAC for ARTHROTEC 50 MG-200 MCG TAB has ranged from a low of $3.5177 (Nov 28, 2013) to a high of $8.5495 (Aug 19, 2026), with a median of $6.1298 per EA.
Are there cheaper alternatives to ARTHROTEC 50 MG-200 MCG TAB?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DICLOFENAC-MISOPROSTOL DR 50-0.2 MG TABLET, is $0.6867 per EA — about 92% below ARTHROTEC 50 MG-200 MCG TAB.
Who manufactures ARTHROTEC 50 MG-200 MCG TAB?
ARTHROTEC 50 MG-200 MCG TAB (NDC 00025141160) is labeled by Pfizer Inc., and CMS classifies it as a brand product.