Product Information
METHADONE 5 MG/5 ML SOLUTION is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.0566 per ML under NDC 00054355563. Its NADAC has been published 308 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AA.
Strength
5 mg/5mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054355563
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
2/19/2025
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087393FDA Approved
Before 1982
TE Code
AA
On Market Since
5/22/1981
Pharmacological Classes
Price Statistics
The NADAC for METHADONE 5 MG/5 ML SOLUTION has been published 308 times since Nov 28, 2013, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0566 per ML |
|---|---|
| All-time high | $0.0669 (Jan 13, 2016) |
| All-time low | $0.0551 (Jul 17, 2024) |
| 52-week high | $0.0566 |
| 52-week low | $0.0566 |
| Median price | $0.0627 |
| Average price | $0.0618 |
| Largest weekly change | -11.0% (Apr 17, 2024) |
| Weeks tracked | 308 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
-13.6%
5Y
-13.6%
All
-1.1%
Last surveyed Feb 11, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Methadone Hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Methadone Hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Opioid Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHADONE 5 MG/5 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE 5 MG/5 ML SOLUTION, manufactured by Hikma Pharmaceuticals USA Inc., is $0.0566 per ML (NDC 00054355563), effective Feb 11, 2026.
How has the price of METHADONE 5 MG/5 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for METHADONE 5 MG/5 ML SOLUTION has held within roughly two percent of its current level. It has been tracked across 308 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHADONE 5 MG/5 ML SOLUTION?
Since Nov 28, 2013, the NADAC for METHADONE 5 MG/5 ML SOLUTION has ranged from a low of $0.0551 (Jul 17, 2024) to a high of $0.0669 (Jan 13, 2016), with a median of $0.0627 per ML.
Are there cheaper alternatives to METHADONE 5 MG/5 ML SOLUTION?
No other NADAC-published product currently shares the active ingredient and strength of METHADONE 5 MG/5 ML SOLUTION in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures METHADONE 5 MG/5 ML SOLUTION?
METHADONE 5 MG/5 ML SOLUTION (NDC 00054355563) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.