Product Information
SYSTANE GEL EYE DROPS is a brand product labeled by Alcon Laboratories, Inc., priced at $1.1302 per ML under NDC 00065045407. Its NADAC has been published 671 times since Nov 28, 2013.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065045407
Classification
Brand
Dosage Form
GEL
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
2/9/2011
Price Statistics
The NADAC for SYSTANE GEL EYE DROPS has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 23.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1302 per ML |
|---|---|
| All-time high | $1.1390 (Nov 12, 2025) |
| All-time low | $0.8990 (Jan 18, 2017) |
| 52-week high | $1.1390 |
| 52-week low | $1.1302 |
| Median price | $0.9743 |
| Average price | $1.0017 |
| Largest weekly change | -7.5% (Nov 23, 2022) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Alcon Laboratories, Inc. manufacturer profile
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Drug market
polyethylene glycol 400 and propylene glycol market comparison
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of SYSTANE GEL EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE GEL EYE DROPS, manufactured by Alcon Laboratories, Inc., is $1.1302 per ML (NDC 00065045407), effective Sep 30, 2026.
How has the price of SYSTANE GEL EYE DROPS changed over time?
Over the history we have for it, the NADAC for SYSTANE GEL EYE DROPS has risen 23.2%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYSTANE GEL EYE DROPS?
Since Nov 28, 2013, the NADAC for SYSTANE GEL EYE DROPS has ranged from a low of $0.8990 (Jan 18, 2017) to a high of $1.1390 (Nov 12, 2025), with a median of $0.9743 per ML.
Are there cheaper alternatives to SYSTANE GEL EYE DROPS?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GENTEAL TEARS SEVERE GEL DROPS, is $1.0898 per ML — about 4% below SYSTANE GEL EYE DROPS.
Who manufactures SYSTANE GEL EYE DROPS?
SYSTANE GEL EYE DROPS (NDC 00065045407) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.