Product Information
SYSTANE COMPLETE 0.6% EYE DROP is a brand product labeled by Alcon Laboratories, Inc., priced at $0.9855 per ML under NDC 00065048111. Its NADAC has been published 376 times since Aug 22, 2018.
Strength
.06 mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065048111
Classification
Brand
Dosage Form
EMULSION
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
1/18/2018
Price Statistics
The NADAC for SYSTANE COMPLETE 0.6% EYE DROP has been published 376 times since Aug 22, 2018, and over the history we have for it it has risen 6.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9855 per ML |
|---|---|
| All-time high | $1.0341 (Nov 15, 2023) |
| All-time low | $0.8301 (Mar 23, 2022) |
| 52-week high | $0.9855 |
| 52-week low | $0.9760 |
| Median price | $0.9821 |
| Average price | $0.9734 |
| Largest weekly change | -14.4% (Feb 23, 2022) |
| Weeks tracked | 376 |
| Tracking since | Aug 22, 2018 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SYSTANE COMPLETE 0.6% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE COMPLETE 0.6% EYE DROP, manufactured by Alcon Laboratories, Inc., is $0.9855 per ML (NDC 00065048111), effective Jun 24, 2026.
How has the price of SYSTANE COMPLETE 0.6% EYE DROP changed over time?
Over the history we have for it, the NADAC for SYSTANE COMPLETE 0.6% EYE DROP has risen 6.8%. It has been tracked across 376 weekly CMS publications since Aug 22, 2018.
What are the highest and lowest recorded NADAC prices for SYSTANE COMPLETE 0.6% EYE DROP?
Since Aug 22, 2018, the NADAC for SYSTANE COMPLETE 0.6% EYE DROP has ranged from a low of $0.8301 (Mar 23, 2022) to a high of $1.0341 (Nov 15, 2023), with a median of $0.9821 per ML.
Are there cheaper alternatives to SYSTANE COMPLETE 0.6% EYE DROP?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as SYSTANE COMPLETE 0.6% EYE DROP, but none are currently priced below it.
Who manufactures SYSTANE COMPLETE 0.6% EYE DROP?
SYSTANE COMPLETE 0.6% EYE DROP (NDC 00065048111) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.
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Same classification