Product Information
SYSTANE ULTRA 0.4-0.3% EYE DRP is a brand product labeled by Alcon Laboratories, Inc., priced at $0.5616 per ML under NDC 00065143118. Its NADAC has been published 222 times since Aug 4, 2021.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065143118
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
10/22/2025
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
10/1/2014
Price Statistics
The NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has been published 222 times since Aug 4, 2021, and over the history we have for it it has risen 10.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5616 per ML |
|---|---|
| All-time high | $0.5699 (Dec 13, 2023) |
| All-time low | $0.4961 (Jan 19, 2022) |
| 52-week high | $0.5616 |
| 52-week low | $0.5577 |
| Median price | $0.5464 |
| Average price | $0.5366 |
| Largest weekly change | +7.9% (Jan 18, 2023) |
| Weeks tracked | 222 |
| Tracking since | Aug 4, 2021 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SYSTANE ULTRA 0.4-0.3% EYE DRP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE ULTRA 0.4-0.3% EYE DRP, manufactured by Alcon Laboratories, Inc., is $0.5616 per ML (NDC 00065143118), effective Oct 29, 2025.
How has the price of SYSTANE ULTRA 0.4-0.3% EYE DRP changed over time?
Over the history we have for it, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has risen 10.1%. It has been tracked across 222 weekly CMS publications since Aug 4, 2021.
What are the highest and lowest recorded NADAC prices for SYSTANE ULTRA 0.4-0.3% EYE DRP?
Since Aug 4, 2021, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has ranged from a low of $0.4961 (Jan 19, 2022) to a high of $0.5699 (Dec 13, 2023), with a median of $0.5464 per ML.
Are there cheaper alternatives to SYSTANE ULTRA 0.4-0.3% EYE DRP?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as SYSTANE ULTRA 0.4-0.3% EYE DRP, but none are currently priced below it.
Who manufactures SYSTANE ULTRA 0.4-0.3% EYE DRP?
SYSTANE ULTRA 0.4-0.3% EYE DRP (NDC 00065143118) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.
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