Product Information
LUPRON DEPOT 22.5 MG 3MO KIT is a brand product labeled by AbbVie Inc., priced at $6516.2982 per EA under NDC 00074334603. Its NADAC has been published 662 times since Nov 28, 2013.
FDA first approved this application on Dec 22, 1995.
The High Outlier badge above means this manufacturer's average price in the leuprolide acetate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Manufacturer
AbbVie Inc.NDC
00074334603
Classification
Brand
Dosage Form
KIT
Effective Date
1/2/2026
Approval Type
New Drug (NDA)
FDA Application
NDA020517FDA Approved
12/22/1995
On Market Since
12/22/1995
Price Statistics
The NADAC for LUPRON DEPOT 22.5 MG 3MO KIT has been published 662 times since Nov 28, 2013, and over the history we have for it it has risen 134.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6516.2982 per EA |
|---|---|
| All-time high | $6516.2982 (Aug 12, 2026) |
| All-time low | $2782.6117 (Nov 28, 2013) |
| 52-week high | $6516.2982 |
| 52-week low | $6205.9983 |
| Median price | $4847.1588 |
| Average price | $4710.4656 |
| Largest weekly change | +9.4% (Jan 10, 2018) |
| Weeks tracked | 662 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LUPRON DEPOT 22.5 MG 3MO KIT?
The current National Average Drug Acquisition Cost (NADAC) for LUPRON DEPOT 22.5 MG 3MO KIT, manufactured by AbbVie Inc., is $6516.2982 per EA (NDC 00074334603), effective Aug 12, 2026.
How has the price of LUPRON DEPOT 22.5 MG 3MO KIT changed over time?
Over the history we have for it, the NADAC for LUPRON DEPOT 22.5 MG 3MO KIT has risen 134.2%. It has been tracked across 662 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LUPRON DEPOT 22.5 MG 3MO KIT?
Since Nov 28, 2013, the NADAC for LUPRON DEPOT 22.5 MG 3MO KIT has ranged from a low of $2782.6117 (Nov 28, 2013) to a high of $6516.2982 (Aug 12, 2026), with a median of $4847.1588 per EA.
Are there cheaper alternatives to LUPRON DEPOT 22.5 MG 3MO KIT?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LEUPROLIDE 2WK 14 MG/2.8 ML KT, is $197.6060 per EA — about 97% below LUPRON DEPOT 22.5 MG 3MO KIT.
Who manufactures LUPRON DEPOT 22.5 MG 3MO KIT?
LUPRON DEPOT 22.5 MG 3MO KIT (NDC 00074334603) is labeled by AbbVie Inc., and CMS classifies it as a brand product.