Product Information
LUPRON DEPOT 3.75 MG KIT is a brand product labeled by AbbVie Inc., priced at $1821.1269 per EA under NDC 00074364103. Its NADAC has been published 663 times since Nov 28, 2013.
FDA first approved this application on Oct 22, 1990.
The High Outlier badge above means this manufacturer's average price in the leuprolide acetate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Manufacturer
AbbVie Inc.NDC
00074364103
Classification
Brand
Dosage Form
KIT
Effective Date
8/19/2026
Approval Type
New Drug (NDA)
FDA Application
NDA020011FDA Approved
10/22/1990
On Market Since
10/22/1990
Price Statistics
The NADAC for LUPRON DEPOT 3.75 MG KIT has been published 663 times since Nov 28, 2013, and over the history we have for it it has risen 134.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1821.1269 per EA |
|---|---|
| All-time high | $1835.6460 (Jun 10, 2026) |
| All-time low | $770.7778 (Dec 18, 2013) |
| 52-week high | $1835.6460 |
| 52-week low | $1738.6550 |
| Median price | $1351.3709 |
| Average price | $1314.2334 |
| Largest weekly change | +9.4% (Jan 10, 2018) |
| Weeks tracked | 663 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 89% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LUPRON DEPOT 3.75 MG KIT?
The current National Average Drug Acquisition Cost (NADAC) for LUPRON DEPOT 3.75 MG KIT, manufactured by AbbVie Inc., is $1821.1269 per EA (NDC 00074364103), effective Aug 19, 2026.
How has the price of LUPRON DEPOT 3.75 MG KIT changed over time?
Over the history we have for it, the NADAC for LUPRON DEPOT 3.75 MG KIT has risen 134.8%. It has been tracked across 663 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LUPRON DEPOT 3.75 MG KIT?
Since Nov 28, 2013, the NADAC for LUPRON DEPOT 3.75 MG KIT has ranged from a low of $770.7778 (Dec 18, 2013) to a high of $1835.6460 (Jun 10, 2026), with a median of $1351.3709 per EA.
Are there cheaper alternatives to LUPRON DEPOT 3.75 MG KIT?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LEUPROLIDE 2WK 14 MG/2.8 ML KT, is $197.6060 per EA — about 89% below LUPRON DEPOT 3.75 MG KIT.
Who manufactures LUPRON DEPOT 3.75 MG KIT?
LUPRON DEPOT 3.75 MG KIT (NDC 00074364103) is labeled by AbbVie Inc., and CMS classifies it as a brand product.