Product Information
LUPRON DEPOT 3.75 MG KIT is a brand product labeled by AbbVie Inc., priced at $1826.7100 per EA under NDC 00074364103. Its NADAC has been published 655 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the leuprolide acetate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Manufacturer
AbbVie Inc.NDC
00074364103
Classification
Brand
Dosage Form
KIT
Last Updated
6/17/2026
Approval Type
New Drug (NDA)
FDA Application
NDA020011On Market Since
10/22/1990
Price Statistics
The NADAC for LUPRON DEPOT 3.75 MG KIT has been published 655 times since Nov 28, 2013, and over the history we have for it it has risen 135.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1826.7100 per EA |
|---|---|
| All-time high | $1835.6460 (Jun 10, 2026) |
| All-time low | $770.7778 (Dec 18, 2013) |
| 52-week high | $1835.6460 |
| 52-week low | $1737.9640 |
| Median price | $1351.3709 |
| Average price | $1308.0055 |
| Largest weekly change | +9.4% (Jan 10, 2018) |
| Weeks tracked | 655 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 89% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of LUPRON DEPOT 3.75 MG KIT?
The current National Average Drug Acquisition Cost (NADAC) for LUPRON DEPOT 3.75 MG KIT, manufactured by AbbVie Inc., is $1826.7100 per EA (NDC 00074364103), effective Jun 24, 2026.
How has the price of LUPRON DEPOT 3.75 MG KIT changed over time?
Over the history we have for it, the NADAC for LUPRON DEPOT 3.75 MG KIT has risen 135.5%. It has been tracked across 655 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LUPRON DEPOT 3.75 MG KIT?
Since Nov 28, 2013, the NADAC for LUPRON DEPOT 3.75 MG KIT has ranged from a low of $770.7778 (Dec 18, 2013) to a high of $1835.6460 (Jun 10, 2026), with a median of $1351.3709 per EA.
Are there cheaper alternatives to LUPRON DEPOT 3.75 MG KIT?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, LEUPROLIDE 2WK 14 MG/2.8 ML KT, is $197.6060 per EA — about 89% below LUPRON DEPOT 3.75 MG KIT.
Who manufactures LUPRON DEPOT 3.75 MG KIT?
LUPRON DEPOT 3.75 MG KIT (NDC 00074364103) is labeled by AbbVie Inc., and CMS classifies it as a brand product.
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