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Historical record - last NADAC effective date: 5/22/2024

Product Information

KALETRA 200-50 MG TABLET is a brand product labeled by AbbVie Inc., priced at $8.3041 per EA under NDC 00074679922. Its NADAC has been published 486 times since Nov 28, 2013.

FDA first approved this application on Oct 28, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

KALETRA 200-50 MG TABLET

Lopinavir and Ritonavir
$8.3041per EA

Strength

200; 50 mg/1; mg/1

Manufacturer

AbbVie Inc.

NDC

00074679922

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

5/22/2024

Active Ingredients

LOPINAVIR; RITONAVIR

Approval Type

New Drug (NDA)

FDA Application

NDA021906

FDA Approved

10/28/2005

TE Code

AB

On Market Since

6/18/2010

Pharmacological Classes

Breast Cancer Resistance Protein Inhibitors
Cytochrome P450 1A2 Inducers
Cytochrome P450 2B6 Inducers
Cytochrome P450 2C19 Inducers
Cytochrome P450 2C9 Inducers
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inducers
Cytochrome P450 3A Inhibitor
Cytochrome P450 3A Inhibitors
Cytochrome P450 3A Inhibitors
Cytochrome P450 3A4 Inhibitors
HIV Protease Inhibitors
HIV Protease Inhibitors
Organic Anion Transporting Polypeptide 1B1 Inhibitors
P-Glycoprotein Inhibitors
P-Glycoprotein Inhibitors
Protease Inhibitor
Protease Inhibitor
UDP Glucuronosyltransferases Inducers

Price Statistics

The NADAC for KALETRA 200-50 MG TABLET has been published 486 times since Nov 28, 2013, and over the history we have for it it has risen 33.2%. The table below summarizes its recorded NADAC range and movement.

Current price$8.3041 per EA
All-time high$8.3532 (Mar 10, 2021)
All-time low$6.1999 (Dec 18, 2013)
Median price$8.2614
Average price$7.7849
Largest weekly change+6.9% (Jan 6, 2016)
Weeks tracked486
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

+0.5%

5Y

+0.5%

All

+33.2%

Last surveyed May 14, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 46% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 46%

2 alternatives • Same active ingredient

LOPINAVIR-RITONAVR 200-50 MG TB
Generic
42385093412•Laurus Labs Limited
$4.4434
Save 46%
KALETRA 200-50 MG TABLET
Brand
00074401412•AbbVie Inc.
$8.3041

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Frequently asked questions

What is the NADAC price of KALETRA 200-50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for KALETRA 200-50 MG TABLET, manufactured by AbbVie Inc., is $8.3041 per EA (NDC 00074679922), effective May 14, 2025.

How has the price of KALETRA 200-50 MG TABLET changed over time?

Over the history we have for it, the NADAC for KALETRA 200-50 MG TABLET has risen 33.2%. It has been tracked across 486 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for KALETRA 200-50 MG TABLET?

Since Nov 28, 2013, the NADAC for KALETRA 200-50 MG TABLET has ranged from a low of $6.1999 (Dec 18, 2013) to a high of $8.3532 (Mar 10, 2021), with a median of $8.2614 per EA.

Are there cheaper alternatives to KALETRA 200-50 MG TABLET?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOPINAVIR-RITONAVR 200-50 MG TB, is $4.4434 per EA — about 46% below KALETRA 200-50 MG TABLET.

Who manufactures KALETRA 200-50 MG TABLET?

KALETRA 200-50 MG TABLET (NDC 00074679922) is labeled by AbbVie Inc., and CMS classifies it as a brand product.