Product Information

LOPINAVIR-RITONAVR 200-50 MG TB is a generic product labeled by Laurus Labs Limited, priced at $4.4434 per EA under NDC 42385093412. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Mar 21, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOPINAVIR-RITONAVR 200-50 MG TB

Lopinavir and Ritonavir
$4.4434per EA

Strength

200; 50 mg/1; mg/1

NDC

42385093412

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LOPINAVIR; RITONAVIR

Approval Type

Generic (ANDA)

FDA Application

ANDA213857

FDA Approved

3/21/2022

TE Code

AB

On Market Since

3/22/2022

Pharmacological Classes

Breast Cancer Resistance Protein Inhibitors
Cytochrome P450 1A2 Inducers
Cytochrome P450 2B6 Inducers
Cytochrome P450 2C19 Inducers
Cytochrome P450 2C9 Inducers
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inducers
Cytochrome P450 3A Inhibitor
Cytochrome P450 3A Inhibitors
Cytochrome P450 3A Inhibitors
Cytochrome P450 3A4 Inhibitors
HIV Protease Inhibitors
HIV Protease Inhibitors
Organic Anion Transporting Polypeptide 1B1 Inhibitors
P-Glycoprotein Inhibitors
P-Glycoprotein Inhibitors
Protease Inhibitor
Protease Inhibitor
UDP Glucuronosyltransferases Inducers

Price Statistics

The NADAC for LOPINAVIR-RITONAVR 200-50 MG TB has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 8.5%. The table below summarizes its recorded NADAC range and movement.

Current price$4.4434 per EA
All-time high$5.3737 (Dec 11, 2024)
All-time low$4.1706 (Jun 19, 2024)
52-week high$5.2427
52-week low$4.3788
Median price$4.5520
Average price$4.6184
Largest weekly change+15.8% (Nov 20, 2024)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+0.5%

1M

+0.5%

3M

+1.5%

6M

-10.0%

1Y

-5.3%

3Y

N/A

5Y

N/A

All

-8.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of LOPINAVIR-RITONAVR 200-50 MG TB?

The current National Average Drug Acquisition Cost (NADAC) for LOPINAVIR-RITONAVR 200-50 MG TB, manufactured by Laurus Labs Limited, is $4.4434 per EA (NDC 42385093412), effective Aug 19, 2026.

How has the price of LOPINAVIR-RITONAVR 200-50 MG TB changed over time?

Over the history we have for it, the NADAC for LOPINAVIR-RITONAVR 200-50 MG TB has declined 8.5%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for LOPINAVIR-RITONAVR 200-50 MG TB?

Since Apr 17, 2024, the NADAC for LOPINAVIR-RITONAVR 200-50 MG TB has ranged from a low of $4.1706 (Jun 19, 2024) to a high of $5.3737 (Dec 11, 2024), with a median of $4.5520 per EA.

Are there cheaper alternatives to LOPINAVIR-RITONAVR 200-50 MG TB?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOPINAVIR-RITONAVR 200-50 MG TB in a comparable dosage form, but none are currently priced below it.

Who manufactures LOPINAVIR-RITONAVR 200-50 MG TB?

LOPINAVIR-RITONAVR 200-50 MG TB (NDC 42385093412) is labeled by Laurus Labs Limited, and CMS classifies it as a generic product.