Product Information
SYNTHROID 125 MCG TABLET is a brand product labeled by AbbVie Inc., priced at $1.6625 per EA under NDC 00074706890. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jul 24, 2002. Its Orange Book therapeutic-equivalence code is AB1,AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
125 ug/1
Manufacturer
AbbVie Inc.NDC
00074706890
Classification
Brand
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LEVOTHYROXINE SODIUMApproval Type
New Drug (NDA)
FDA Application
NDA021402FDA Approved
7/24/2002
TE Code
AB1,AB2
On Market Since
7/24/2002
Pharmacological Classes
Price Statistics
The NADAC for SYNTHROID 125 MCG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 113.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.6625 per EA |
|---|---|
| All-time high | $1.6653 (Jun 10, 2026) |
| All-time low | $0.7786 (Nov 28, 2013) |
| 52-week high | $1.6653 |
| 52-week low | $1.5843 |
| Median price | $1.2470 |
| Average price | $1.2482 |
| Largest weekly change | +9.8% (Jul 9, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SYNTHROID 125 MCG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SYNTHROID 125 MCG TABLET, manufactured by AbbVie Inc., is $1.6625 per EA (NDC 00074706890), effective Aug 19, 2026.
How has the price of SYNTHROID 125 MCG TABLET changed over time?
Over the history we have for it, the NADAC for SYNTHROID 125 MCG TABLET has risen 113.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYNTHROID 125 MCG TABLET?
Since Nov 28, 2013, the NADAC for SYNTHROID 125 MCG TABLET has ranged from a low of $0.7786 (Nov 28, 2013) to a high of $1.6653 (Jun 10, 2026), with a median of $1.2470 per EA.
Are there cheaper alternatives to SYNTHROID 125 MCG TABLET?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LEVOTHYROXINE 125 MCG TABLET, is $0.0570 per EA — about 97% below SYNTHROID 125 MCG TABLET.
Who manufactures SYNTHROID 125 MCG TABLET?
SYNTHROID 125 MCG TABLET (NDC 00074706890) is labeled by AbbVie Inc., and CMS classifies it as a brand product.