Product Information

AZOPT 1% EYE DROPS is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $35.1697 per ML under NDC 00078072210. Its NADAC has been published 205 times since Mar 30, 2022.

FDA first approved this application on Apr 1, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

AZOPT 1% EYE DROPS

brinzolamide
$35.1697per ML
Discontinued

Strength

10 mg/mL

NDC

00078072210

Classification

Brand

Dosage Form

SUSPENSION/ DROPS

Route

OPHTHALMIC

Effective Date

2/18/2026

Active Ingredients

BRINZOLAMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA020816

FDA Approved

4/1/1998

TE Code

AB

On Market Since

4/30/1998

Pharmacological Classes

Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitors

Price Statistics

The NADAC for AZOPT 1% EYE DROPS has been published 205 times since Mar 30, 2022, and over the history we have for it it has risen 6.8%. The table below summarizes its recorded NADAC range and movement.

Current price$35.1697 per ML
All-time high$35.4168 (Jul 10, 2024)
All-time low$32.9151 (Mar 30, 2022)
52-week high$35.2070
52-week low$35.1619
Median price$34.7220
Average price$34.7480
Largest weekly change+5.0% (Aug 3, 2022)
Weeks tracked205
Tracking sinceMar 30, 2022

Price History

1W

N/A

1M

N/A

3M

N/A

6M

0.0%

1Y

-0.1%

3Y

+2.0%

5Y

N/A

All

+6.8%

Last surveyed Feb 25, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 73% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AZOPT 1% EYE DROPS?

The current National Average Drug Acquisition Cost (NADAC) for AZOPT 1% EYE DROPS, manufactured by Novartis Pharmaceuticals Corporation, is $35.1697 per ML (NDC 00078072210), effective Feb 25, 2026.

How has the price of AZOPT 1% EYE DROPS changed over time?

Over the history we have for it, the NADAC for AZOPT 1% EYE DROPS has risen 6.8%. It has been tracked across 205 weekly CMS publications since Mar 30, 2022.

What are the highest and lowest recorded NADAC prices for AZOPT 1% EYE DROPS?

Since Mar 30, 2022, the NADAC for AZOPT 1% EYE DROPS has ranged from a low of $32.9151 (Mar 30, 2022) to a high of $35.4168 (Jul 10, 2024), with a median of $34.7220 per ML.

Are there cheaper alternatives to AZOPT 1% EYE DROPS?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BRINZOLAMIDE 1% EYE DROPS, is $9.4893 per ML — about 73% below AZOPT 1% EYE DROPS.

Who manufactures AZOPT 1% EYE DROPS?

AZOPT 1% EYE DROPS (NDC 00078072210) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.