Product Information
SIMBRINZA 1%-0.2% EYE DROP is a brand product labeled by Alcon Laboratories, Inc., priced at $26.0392 per ML under NDC 00065414727. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Apr 19, 2013.
Strength
2; 10 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065414727
Classification
Brand
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
BRIMONIDINE TARTRATE; BRINZOLAMIDEApproval Type
New Drug (NDA)
FDA Application
NDA204251FDA Approved
4/19/2013
On Market Since
5/6/2013
Pharmacological Classes
Price Statistics
The NADAC for SIMBRINZA 1%-0.2% EYE DROP has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 145.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $26.0392 per ML |
|---|---|
| All-time high | $26.0684 (May 13, 2026) |
| All-time low | $10.6251 (Nov 28, 2013) |
| 52-week high | $26.0684 |
| 52-week low | $25.2900 |
| Median price | $20.5570 |
| Average price | $19.8833 |
| Largest weekly change | +9.5% (Oct 15, 2014) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the brinzolamide/brimonidine tartrate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Alcon Laboratories, Inc. manufacturer profile
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Drug market
brinzolamide/brimonidine tartrate market comparison
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Therapeutic class
Carbonic Anhydrase Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SIMBRINZA 1%-0.2% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for SIMBRINZA 1%-0.2% EYE DROP, manufactured by Alcon Laboratories, Inc., is $26.0392 per ML (NDC 00065414727), effective Sep 30, 2026.
How has the price of SIMBRINZA 1%-0.2% EYE DROP changed over time?
Over the history we have for it, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has risen 145.1%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SIMBRINZA 1%-0.2% EYE DROP?
Since Nov 28, 2013, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has ranged from a low of $10.6251 (Nov 28, 2013) to a high of $26.0684 (May 13, 2026), with a median of $20.5570 per ML.
Are there cheaper alternatives to SIMBRINZA 1%-0.2% EYE DROP?
No other NADAC-published product currently shares the active ingredient and strength of SIMBRINZA 1%-0.2% EYE DROP in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures SIMBRINZA 1%-0.2% EYE DROP?
SIMBRINZA 1%-0.2% EYE DROP (NDC 00065414727) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.