Product Information
SIMBRINZA 1%-0.2% EYE DROP is a brand product labeled by Alcon Laboratories, Inc., priced at $26.0378 per ML under NDC 00065414727. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Apr 19, 2013.
Strength
2; 10 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065414727
Classification
Brand
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
BRIMONIDINE TARTRATE; BRINZOLAMIDEApproval Type
New Drug (NDA)
FDA Application
NDA204251FDA Approved
4/19/2013
On Market Since
5/6/2013
Pharmacological Classes
Price Statistics
The NADAC for SIMBRINZA 1%-0.2% EYE DROP has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 145.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $26.0378 per ML |
|---|---|
| All-time high | $26.0684 (May 13, 2026) |
| All-time low | $10.6251 (Nov 28, 2013) |
| 52-week high | $26.0684 |
| 52-week low | $25.2900 |
| Median price | $20.5570 |
| Average price | $19.8278 |
| Largest weekly change | +9.5% (Oct 15, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the brinzolamide/brimonidine tartrate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SIMBRINZA 1%-0.2% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for SIMBRINZA 1%-0.2% EYE DROP, manufactured by Alcon Laboratories, Inc., is $26.0378 per ML (NDC 00065414727), effective Aug 19, 2026.
How has the price of SIMBRINZA 1%-0.2% EYE DROP changed over time?
Over the history we have for it, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has risen 145.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SIMBRINZA 1%-0.2% EYE DROP?
Since Nov 28, 2013, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has ranged from a low of $10.6251 (Nov 28, 2013) to a high of $26.0684 (May 13, 2026), with a median of $20.5570 per ML.
Are there cheaper alternatives to SIMBRINZA 1%-0.2% EYE DROP?
No other NADAC-published product currently shares the active ingredient and strength of SIMBRINZA 1%-0.2% EYE DROP in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures SIMBRINZA 1%-0.2% EYE DROP?
SIMBRINZA 1%-0.2% EYE DROP (NDC 00065414727) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.