Product Information

SIMBRINZA 1%-0.2% EYE DROP is a brand product labeled by Alcon Laboratories, Inc., priced at $26.0412 per ML under NDC 00065414727. Its NADAC has been published 657 times since Nov 28, 2013.

SIMBRINZA 1%-0.2% EYE DROP

brinzolamide/brimonidine tartrate
$26.0412per ML

Strength

2; 10 mg/mL; mg/mL

NDC

00065414727

Classification

Brand

Dosage Form

SUSPENSION/ DROPS

Route

OPHTHALMIC

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA204251

On Market Since

5/6/2013

Pharmacological Classes

Adrenergic alpha-Agonists
Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitors
alpha-Adrenergic Agonist

Price Statistics

The NADAC for SIMBRINZA 1%-0.2% EYE DROP has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 145.1%. The table below summarizes its recorded NADAC range and movement.

Current price$26.0412 per ML
All-time high$26.0684 (May 13, 2026)
All-time low$10.6251 (Nov 28, 2013)
52-week high$26.0684
52-week low$25.2833
Median price$20.5570
Average price$19.7521
Largest weekly change+9.5% (Oct 15, 2014)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+0.0%

3M

-0.1%

6M

+2.9%

1Y

+3.0%

3Y

+9.3%

5Y

+19.6%

All

+145.1%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the brinzolamide/brimonidine tartrate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of SIMBRINZA 1%-0.2% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for SIMBRINZA 1%-0.2% EYE DROP, manufactured by Alcon Laboratories, Inc., is $26.0412 per ML (NDC 00065414727), effective Jun 24, 2026.

How has the price of SIMBRINZA 1%-0.2% EYE DROP changed over time?

Over the history we have for it, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has risen 145.1%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SIMBRINZA 1%-0.2% EYE DROP?

Since Nov 28, 2013, the NADAC for SIMBRINZA 1%-0.2% EYE DROP has ranged from a low of $10.6251 (Nov 28, 2013) to a high of $26.0684 (May 13, 2026), with a median of $20.5570 per ML.

Are there cheaper alternatives to SIMBRINZA 1%-0.2% EYE DROP?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of SIMBRINZA 1%-0.2% EYE DROP, so no direct lower-cost alternative is listed.

Who manufactures SIMBRINZA 1%-0.2% EYE DROP?

SIMBRINZA 1%-0.2% EYE DROP (NDC 00065414727) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.