Product Information

XIIDRA 5% EYE DROPS is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $11.8311 per EA under NDC 00078091112. Its NADAC has been published 302 times since Nov 11, 2020.

FDA first approved this application on Jul 11, 2016.

XIIDRA 5% EYE DROPS

Lifitegrast
$11.8311per EA

Strength

50 mg/mL

NDC

00078091112

Classification

Brand

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

LIFITEGRAST

Approval Type

New Drug (NDA)

FDA Application

NDA208073

FDA Approved

7/11/2016

On Market Since

7/11/2016

Pharmacological Classes

Lymphocyte Function-Associated Antigen-1 Antagonist
Lymphocyte Function-Associated Antigen-1 Antagonists

Price Statistics

The NADAC for XIIDRA 5% EYE DROPS has been published 302 times since Nov 11, 2020, and over the history we have for it it has risen 33.5%. The table below summarizes its recorded NADAC range and movement.

Current price$11.8311 per EA
All-time high$11.8386 (May 13, 2026)
All-time low$8.8473 (Dec 23, 2020)
52-week high$11.8386
52-week low$11.4891
Median price$10.9471
Average price$10.7319
Largest weekly change+8.0% (Jan 11, 2023)
Weeks tracked302
Tracking sinceNov 11, 2020

Price History

1W

+0.0%

1M

+0.0%

3M

+0.0%

6M

-0.1%

1Y

+3.0%

3Y

+8.1%

5Y

+25.0%

All

+33.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Related Drugs

Same classification

No related drugs found.

Frequently asked questions

What is the NADAC price of XIIDRA 5% EYE DROPS?

The current National Average Drug Acquisition Cost (NADAC) for XIIDRA 5% EYE DROPS, manufactured by Novartis Pharmaceuticals Corporation, is $11.8311 per EA (NDC 00078091112), effective Aug 19, 2026.

How has the price of XIIDRA 5% EYE DROPS changed over time?

Over the history we have for it, the NADAC for XIIDRA 5% EYE DROPS has risen 33.5%. It has been tracked across 302 weekly CMS publications since Nov 11, 2020.

What are the highest and lowest recorded NADAC prices for XIIDRA 5% EYE DROPS?

Since Nov 11, 2020, the NADAC for XIIDRA 5% EYE DROPS has ranged from a low of $8.8473 (Dec 23, 2020) to a high of $11.8386 (May 13, 2026), with a median of $10.9471 per EA.

Are there cheaper alternatives to XIIDRA 5% EYE DROPS?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as XIIDRA 5% EYE DROPS in a comparable dosage form, but none are currently priced below it.

Who manufactures XIIDRA 5% EYE DROPS?

XIIDRA 5% EYE DROPS (NDC 00078091112) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.