Product Information
PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP is a generic product labeled by Xttrium Laboratories, Inc., priced at $0.0383 per ML under NDC 00116402416. Its NADAC has been published 58 times since May 28, 2025.
PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP
Promethazine Hydrochloride and Dextromethorphan HydrobromideStrength
15; 6.25 mg/5mL; mg/5mL
Manufacturer
Xttrium Laboratories, Inc.NDC
00116402416
Classification
Generic
Dosage Form
SYRUP
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
DEXTROMETHORPHAN HYDROBROMIDE; PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA088864On Market Since
4/7/2025
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP has been published 58 times since May 28, 2025, and over the history we have for it it has declined 21.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0383 per ML |
|---|---|
| All-time high | $0.0487 (Jun 11, 2025) |
| All-time low | $0.0383 (Jun 17, 2026) |
| 52-week high | $0.0487 |
| 52-week low | $0.0383 |
| Median price | $0.0431 |
| Average price | $0.0428 |
| Largest weekly change | -6.0% (Jul 23, 2025) |
| Weeks tracked | 58 |
| Tracking since | May 28, 2025 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP, manufactured by Xttrium Laboratories, Inc., is $0.0383 per ML (NDC 00116402416), effective Jul 1, 2026.
How has the price of PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP has declined 21.3%. It has been tracked across 58 weekly CMS publications since May 28, 2025.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP?
Since May 28, 2025, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP has ranged from a low of $0.0383 (Jun 17, 2026) to a high of $0.0487 (Jun 11, 2025), with a median of $0.0431 per ML.
Are there cheaper alternatives to PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP?
5 NADAC-published products share the same active ingredient, strength, and dosage form as PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP, but none are currently priced below it.
Who manufactures PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP?
PROMETHAZINE-DM 6.25-15 MG/5 ML SYRUP (NDC 00116402416) is labeled by Xttrium Laboratories, Inc., and CMS classifies it as a generic product.
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