Product Information
METOCLOPRAMIDE 5 MG/5 ML SOLN is a generic product labeled by PAI Holdings LLC, priced at $0.1273 per ML under NDC 00121057616. Its NADAC has been published 640 times since Nov 28, 2013.
FDA first approved this application on May 28, 1991. Its Orange Book therapeutic-equivalence code is AA.
Strength
5 mg/5mL
Manufacturer
PAI Holdings LLCNDC
00121057616
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
2/18/2026
Active Ingredients
METOCLOPRAMIDE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA072744FDA Approved
5/28/1991
TE Code
AA
On Market Since
6/1/1991
Pharmacological Classes
Price Statistics
The NADAC for METOCLOPRAMIDE 5 MG/5 ML SOLN has been published 640 times since Nov 28, 2013, and over the history we have for it it has risen 992.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1273 per ML |
|---|---|
| All-time high | $0.1315 (Jan 14, 2026) |
| All-time low | $0.0106 (Oct 19, 2016) |
| 52-week high | $0.1315 |
| 52-week low | $0.1101 |
| Median price | $0.0366 |
| Average price | $0.0331 |
| Largest weekly change | +113.9% (Nov 22, 2017) |
| Weeks tracked | 640 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+15.7%
3Y
+233.5%
5Y
+243.2%
All
+992.0%
Last surveyed Feb 25, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
PAI Holdings LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
metoclopramide hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Dopamine-2 Receptor Antagonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METOCLOPRAMIDE 5 MG/5 ML SOLN?
The current National Average Drug Acquisition Cost (NADAC) for METOCLOPRAMIDE 5 MG/5 ML SOLN, manufactured by PAI Holdings LLC, is $0.1273 per ML (NDC 00121057616), effective Feb 25, 2026.
How has the price of METOCLOPRAMIDE 5 MG/5 ML SOLN changed over time?
Over the history we have for it, the NADAC for METOCLOPRAMIDE 5 MG/5 ML SOLN has risen 992.0%. It has been tracked across 640 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METOCLOPRAMIDE 5 MG/5 ML SOLN?
Since Nov 28, 2013, the NADAC for METOCLOPRAMIDE 5 MG/5 ML SOLN has ranged from a low of $0.0106 (Oct 19, 2016) to a high of $0.1315 (Jan 14, 2026), with a median of $0.0366 per ML.
Are there cheaper alternatives to METOCLOPRAMIDE 5 MG/5 ML SOLN?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METOCLOPRAMIDE 5 MG/5 ML SOLN, is $0.1257 per ML — about 1% below METOCLOPRAMIDE 5 MG/5 ML SOLN.
Who manufactures METOCLOPRAMIDE 5 MG/5 ML SOLN?
METOCLOPRAMIDE 5 MG/5 ML SOLN (NDC 00121057616) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.