Product Information

ADVAIR HFA 115-21 MCG INHALER is a brand product labeled by GlaxoSmithKline LLC, priced at $18.7383 per GM under NDC 00173071622. Its NADAC has been published 519 times since Nov 28, 2013.

ADVAIR HFA 115-21 MCG INHALER

fluticasone propionate and salmeterol xinafoate
$18.7383per GM

Strength

115; 21 ug/1; ug/1

NDC

00173071622

Classification

Brand

Dosage Form

AEROSOL, METERED

Route

RESPIRATORY (INHALATION)

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA021254

On Market Since

9/29/2008

Pharmacological Classes

Adrenergic beta2-Agonists
Corticosteroid Hormone Receptor Agonists
Corticosteroid
beta2-Adrenergic Agonist

Price Statistics

The NADAC for ADVAIR HFA 115-21 MCG INHALER has been published 519 times since Nov 28, 2013, and over the history we have for it it has risen 7.2%. The table below summarizes its recorded NADAC range and movement.

Current price$18.7383 per GM
All-time high$26.3818 (Jun 15, 2022)
All-time low$17.4778 (Nov 28, 2013)
52-week high$18.7870
52-week low$18.6826
Median price$21.7865
Average price$22.1037
Largest weekly change-29.0% (Apr 17, 2024)
Weeks tracked519
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+0.0%

3M

+0.1%

6M

+0.0%

1Y

-0.1%

3Y

-29.0%

5Y

-29.0%

All

+7.2%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ADVAIR HFA 115-21 MCG INHALER?

The current National Average Drug Acquisition Cost (NADAC) for ADVAIR HFA 115-21 MCG INHALER, manufactured by GlaxoSmithKline LLC, is $18.7383 per GM (NDC 00173071622), effective Jun 24, 2026.

How has the price of ADVAIR HFA 115-21 MCG INHALER changed over time?

Over the history we have for it, the NADAC for ADVAIR HFA 115-21 MCG INHALER has risen 7.2%. It has been tracked across 519 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ADVAIR HFA 115-21 MCG INHALER?

Since Nov 28, 2013, the NADAC for ADVAIR HFA 115-21 MCG INHALER has ranged from a low of $17.4778 (Nov 28, 2013) to a high of $26.3818 (Jun 15, 2022), with a median of $21.7865 per GM.

Are there cheaper alternatives to ADVAIR HFA 115-21 MCG INHALER?

2 NADAC-published products share the same active ingredient, strength, and dosage form as ADVAIR HFA 115-21 MCG INHALER, but none are currently priced below it.

Who manufactures ADVAIR HFA 115-21 MCG INHALER?

ADVAIR HFA 115-21 MCG INHALER (NDC 00173071622) is labeled by GlaxoSmithKline LLC, and CMS classifies it as a brand product.