Product Information
FLUTICASONE-SALMETEROL 115-21 is a generic product labeled by Prasco Laboratories, priced at $20.6530 per GM under NDC 66993008796. Its NADAC has been published 158 times since Jun 21, 2023.
Strength
115; 21 ug/1; ug/1
Manufacturer
Prasco LaboratoriesNDC
66993008796
Classification
Generic
Dosage Form
AEROSOL, METERED
Route
RESPIRATORY (INHALATION)
Last Updated
6/17/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021254On Market Since
3/1/2023
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 115-21 has been published 158 times since Jun 21, 2023, and over the history we have for it it has risen 3.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $20.6530 per GM |
|---|---|
| All-time high | $21.3592 (Feb 11, 2026) |
| All-time low | $18.6711 (Jul 17, 2024) |
| 52-week high | $21.3592 |
| 52-week low | $20.1519 |
| Median price | $20.5567 |
| Average price | $20.4155 |
| Largest weekly change | -7.9% (Nov 20, 2024) |
| Weeks tracked | 158 |
| Tracking since | Jun 21, 2023 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 9% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 115-21?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 115-21, manufactured by Prasco Laboratories, is $20.6530 per GM (NDC 66993008796), effective Jun 24, 2026.
How has the price of FLUTICASONE-SALMETEROL 115-21 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 115-21 has risen 3.0%. It has been tracked across 158 weekly CMS publications since Jun 21, 2023.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 115-21?
Since Jun 21, 2023, the NADAC for FLUTICASONE-SALMETEROL 115-21 has ranged from a low of $18.6711 (Jul 17, 2024) to a high of $21.3592 (Feb 11, 2026), with a median of $20.5567 per GM.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 115-21?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, ADVAIR HFA 115-21 MCG INHALER, is $18.7383 per GM — about 9% below FLUTICASONE-SALMETEROL 115-21.
Who manufactures FLUTICASONE-SALMETEROL 115-21?
FLUTICASONE-SALMETEROL 115-21 (NDC 66993008796) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.
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