Product Information
SYMBICORT 80-4.5 MCG INHALER is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $19.2330 per GM under NDC 00186037220. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jul 21, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
80; 4.5 ug/1; ug/1
Manufacturer
AstraZeneca Pharmaceuticals LPNDC
00186037220
Classification
Brand
Dosage Form
AEROSOL
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
BUDESONIDE; FORMOTEROL FUMARATEApproval Type
New Drug (NDA)
FDA Application
NDA021929FDA Approved
7/21/2006
TE Code
AB
On Market Since
5/29/2007
Pharmacological Classes
Price Statistics
The NADAC for SYMBICORT 80-4.5 MCG INHALER has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 2.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $19.2330 per GM |
|---|---|
| All-time high | $32.1268 (Jan 3, 2024) |
| All-time low | $19.2330 (Aug 19, 2026) |
| 52-week high | $19.2715 |
| 52-week low | $19.2330 |
| Median price | $25.4470 |
| Average price | $25.5292 |
| Largest weekly change | -40.0% (Jan 10, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SYMBICORT 80-4.5 MCG INHALER?
The current National Average Drug Acquisition Cost (NADAC) for SYMBICORT 80-4.5 MCG INHALER, manufactured by AstraZeneca Pharmaceuticals LP, is $19.2330 per GM (NDC 00186037220), effective Aug 19, 2026.
How has the price of SYMBICORT 80-4.5 MCG INHALER changed over time?
Over the history we have for it, the NADAC for SYMBICORT 80-4.5 MCG INHALER has declined 2.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYMBICORT 80-4.5 MCG INHALER?
Since Nov 28, 2013, the NADAC for SYMBICORT 80-4.5 MCG INHALER has ranged from a low of $19.2330 (Aug 19, 2026) to a high of $32.1268 (Jan 3, 2024), with a median of $25.4470 per GM.
Are there cheaper alternatives to SYMBICORT 80-4.5 MCG INHALER?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUDESONIDE-FORMOTEROL 80-4.5, is $15.8173 per GM — about 18% below SYMBICORT 80-4.5 MCG INHALER.
Who manufactures SYMBICORT 80-4.5 MCG INHALER?
SYMBICORT 80-4.5 MCG INHALER (NDC 00186037220) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.