Product Information
SYMBICORT 80-4.5 MCG INHALER is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $19.2828 per GM under NDC 00186037228. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Jul 21, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
80; 4.5 ug/1; ug/1
Manufacturer
AstraZeneca Pharmaceuticals LPNDC
00186037228
Classification
Brand
Dosage Form
AEROSOL
Route
RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
BUDESONIDE; FORMOTEROL FUMARATEApproval Type
New Drug (NDA)
FDA Application
NDA021929FDA Approved
7/21/2006
TE Code
AB
On Market Since
5/29/2007
Pharmacological Classes
Price Statistics
The NADAC for SYMBICORT 80-4.5 MCG INHALER has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 2.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $19.2828 per GM |
|---|---|
| All-time high | $32.1277 (Jan 3, 2024) |
| All-time low | $19.1736 (May 22, 2024) |
| 52-week high | $19.2844 |
| 52-week low | $19.2046 |
| Median price | $25.3472 |
| Average price | $25.4186 |
| Largest weekly change | -40.0% (Jan 10, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AstraZeneca Pharmaceuticals LP manufacturer profile
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Drug market
Budesonide and Formoterol Fumarate Dihydrate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SYMBICORT 80-4.5 MCG INHALER?
The current National Average Drug Acquisition Cost (NADAC) for SYMBICORT 80-4.5 MCG INHALER, manufactured by AstraZeneca Pharmaceuticals LP, is $19.2828 per GM (NDC 00186037228), effective Sep 30, 2026.
How has the price of SYMBICORT 80-4.5 MCG INHALER changed over time?
Over the history we have for it, the NADAC for SYMBICORT 80-4.5 MCG INHALER has declined 2.7%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYMBICORT 80-4.5 MCG INHALER?
Since Nov 28, 2013, the NADAC for SYMBICORT 80-4.5 MCG INHALER has ranged from a low of $19.1736 (May 22, 2024) to a high of $32.1277 (Jan 3, 2024), with a median of $25.3472 per GM.
Are there cheaper alternatives to SYMBICORT 80-4.5 MCG INHALER?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUDESONIDE-FORMOTEROL 80-4.5, is $15.6684 per GM — about 19% below SYMBICORT 80-4.5 MCG INHALER.
Who manufactures SYMBICORT 80-4.5 MCG INHALER?
SYMBICORT 80-4.5 MCG INHALER (NDC 00186037228) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.