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Product Information

APLENZIN ER 348 MG TABLET is a brand product labeled by Bausch Health US LLC, priced at $93.5116 per EA under NDC 00187581130. Its NADAC has been published 330 times since May 13, 2015.

FDA first approved this application on Apr 23, 2008.

APLENZIN ER 348 MG TABLET

bupropion hydrobromide
$93.5116per EA

Strength

348 mg/1

NDC

00187581130

Classification

Brand

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

9/17/2025

Active Ingredients

BUPROPION HYDROBROMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA022108

FDA Approved

4/23/2008

On Market Since

4/23/2008

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for APLENZIN ER 348 MG TABLET has been published 330 times since May 13, 2015, and over the history we have for it it has risen 232.1%. The table below summarizes its recorded NADAC range and movement.

Current price$93.5116 per EA
All-time high$93.6147 (Aug 13, 2025)
All-time low$28.1591 (May 13, 2015)
52-week high$93.5419
52-week low$93.5116
Median price$72.8055
Average price$73.6910
Largest weekly change+106.1% (Jul 17, 2019)
Weeks tracked330
Tracking sinceMay 13, 2015

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-0.0%

3Y

+20.4%

5Y

+38.4%

All

+232.1%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the bupropion hydrobromide market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of APLENZIN ER 348 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for APLENZIN ER 348 MG TABLET, manufactured by Bausch Health US LLC, is $93.5116 per EA (NDC 00187581130), effective Oct 1, 2025.

How has the price of APLENZIN ER 348 MG TABLET changed over time?

Over the history we have for it, the NADAC for APLENZIN ER 348 MG TABLET has risen 232.1%. It has been tracked across 330 weekly CMS publications since May 13, 2015.

What are the highest and lowest recorded NADAC prices for APLENZIN ER 348 MG TABLET?

Since May 13, 2015, the NADAC for APLENZIN ER 348 MG TABLET has ranged from a low of $28.1591 (May 13, 2015) to a high of $93.6147 (Aug 13, 2025), with a median of $72.8055 per EA.

Are there cheaper alternatives to APLENZIN ER 348 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of APLENZIN ER 348 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures APLENZIN ER 348 MG TABLET?

APLENZIN ER 348 MG TABLET (NDC 00187581130) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.