Product Information

LAMOTRIGINE ER 50 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.5941 per EA under NDC 00228143503. Its NADAC has been published 543 times since May 11, 2016.

FDA first approved this application on Oct 17, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LAMOTRIGINE ER 50 MG TABLET

Lamotrigine
$0.5941per EA
Discontinued

Strength

50 mg/1

NDC

00228143503

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

LAMOTRIGINE

Approval Type

Generic (ANDA)

FDA Application

ANDA200672

FDA Approved

10/17/2013

TE Code

AB

On Market Since

4/1/2016

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Dihydrofolate Reductase Inhibitors
Mood Stabilizer
Organic Cation Transporter 2 Inhibitors

Price Statistics

The NADAC for LAMOTRIGINE ER 50 MG TABLET has been published 543 times since May 11, 2016, and over the history we have for it it has declined 90.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5941 per EA
All-time high$6.9906 (Nov 16, 2016)
All-time low$0.4730 (Nov 20, 2024)
52-week high$0.7246
52-week low$0.5125
Median price$2.1906
Average price$2.4721
Largest weekly change+66.9% (Aug 21, 2024)
Weeks tracked543
Tracking sinceMay 11, 2016

Price History

1W

0.0%

1M

+13.3%

3M

+9.0%

6M

-5.5%

1Y

-18.0%

3Y

-42.0%

5Y

-76.4%

All

-90.6%

Generic Alternatives

The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of LAMOTRIGINE ER 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LAMOTRIGINE ER 50 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.5941 per EA (NDC 00228143503), effective Sep 30, 2026.

How has the price of LAMOTRIGINE ER 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for LAMOTRIGINE ER 50 MG TABLET has declined 90.6%. It has been tracked across 543 weekly CMS publications since May 11, 2016.

What are the highest and lowest recorded NADAC prices for LAMOTRIGINE ER 50 MG TABLET?

Since May 11, 2016, the NADAC for LAMOTRIGINE ER 50 MG TABLET has ranged from a low of $0.4730 (Nov 20, 2024) to a high of $6.9906 (Nov 16, 2016), with a median of $2.1906 per EA.

Are there cheaper alternatives to LAMOTRIGINE ER 50 MG TABLET?

8 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LAMOTRIGINE ER 50 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures LAMOTRIGINE ER 50 MG TABLET?

LAMOTRIGINE ER 50 MG TABLET (NDC 00228143503) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.