Product Information

LAMOTRIGINE ODT 50 MG TABLET is a generic product labeled by Endo USA Inc., priced at $1.2753 per EA under NDC 49884048511. Its NADAC has been published 547 times since Mar 2, 2016.

FDA first approved this application on Oct 27, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Lamotrigine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

LAMOTRIGINE ODT 50 MG TABLET

Lamotrigine
$1.2753per EA
High Outlier

Strength

50 mg/1

Manufacturer

Endo USA Inc.

NDC

49884048511

Classification

Generic

Dosage Form

TABLET, ORALLY DISINTEGRATING

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LAMOTRIGINE

Approval Type

Generic (ANDA)

FDA Application

ANDA204158

FDA Approved

10/27/2015

TE Code

AB

On Market Since

12/16/2015

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Dihydrofolate Reductase Inhibitors
Mood Stabilizer
Organic Cation Transporter 2 Inhibitors

Price Statistics

The NADAC for LAMOTRIGINE ODT 50 MG TABLET has been published 547 times since Mar 2, 2016, and over the history we have for it it has declined 81.2%. The table below summarizes its recorded NADAC range and movement.

Current price$1.2753 per EA
All-time high$7.0944 (Jun 15, 2016)
All-time low$1.2753 (Aug 19, 2026)
52-week high$1.7519
52-week low$1.2753
Median price$4.8241
Average price$4.2218
Largest weekly change+55.3% (Mar 22, 2023)
Weeks tracked547
Tracking sinceMar 2, 2016

Price History

1W

-11.2%

1M

-11.2%

3M

-20.1%

6M

-17.1%

1Y

-27.2%

3Y

-43.7%

5Y

-75.8%

All

-81.2%

Generic Alternatives

The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 59% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LAMOTRIGINE ODT 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LAMOTRIGINE ODT 50 MG TABLET, manufactured by Endo USA Inc., is $1.2753 per EA (NDC 49884048511), effective Aug 19, 2026.

How has the price of LAMOTRIGINE ODT 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for LAMOTRIGINE ODT 50 MG TABLET has declined 81.2%. It has been tracked across 547 weekly CMS publications since Mar 2, 2016.

What are the highest and lowest recorded NADAC prices for LAMOTRIGINE ODT 50 MG TABLET?

Since Mar 2, 2016, the NADAC for LAMOTRIGINE ODT 50 MG TABLET has ranged from a low of $1.2753 (Aug 19, 2026) to a high of $7.0944 (Jun 15, 2016), with a median of $4.8241 per EA.

Are there cheaper alternatives to LAMOTRIGINE ODT 50 MG TABLET?

Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LAMOTRIGINE ER 50 MG TABLET, is $0.5242 per EA — about 59% below LAMOTRIGINE ODT 50 MG TABLET.

Who manufactures LAMOTRIGINE ODT 50 MG TABLET?

LAMOTRIGINE ODT 50 MG TABLET (NDC 49884048511) is labeled by Endo USA Inc., and CMS classifies it as a generic product.