Product Information
GUANFACINE HCL ER 2 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1477 per EA under NDC 00228285111. Its NADAC has been published 607 times since Feb 18, 2015.
FDA first approved this application on Oct 5, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00228285111
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA200881FDA Approved
10/5/2012
TE Code
AB
On Market Since
12/1/2014
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 2 MG TABLET has been published 607 times since Feb 18, 2015, and over the history we have for it it has declined 98.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1477 per EA |
|---|---|
| All-time high | $8.4335 (May 13, 2015) |
| All-time low | $0.1477 (Sep 23, 2026) |
| 52-week high | $0.2166 |
| 52-week low | $0.1477 |
| Median price | $0.3418 |
| Average price | $0.6530 |
| Largest weekly change | -93.7% (Jul 22, 2015) |
| Weeks tracked | 607 |
| Tracking since | Feb 18, 2015 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
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Drug market
guanfacine market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 2 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1477 per EA (NDC 00228285111), effective Sep 30, 2026.
How has the price of GUANFACINE HCL ER 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 2 MG TABLET has declined 98.2%. It has been tracked across 607 weekly CMS publications since Feb 18, 2015.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 2 MG TABLET?
Since Feb 18, 2015, the NADAC for GUANFACINE HCL ER 2 MG TABLET has ranged from a low of $0.1477 (Sep 23, 2026) to a high of $8.4335 (May 13, 2015), with a median of $0.3418 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 2 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GUANFACINE HCL ER 2 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures GUANFACINE HCL ER 2 MG TABLET?
GUANFACINE HCL ER 2 MG TABLET (NDC 00228285111) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.