Product Information
CLONIDINE HCL ER 0.1 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.2117 per EA under NDC 00228424106. Its NADAC has been published 586 times since Jul 15, 2015.
FDA first approved this application on May 15, 2015. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00228424106
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CLONIDINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA203320FDA Approved
5/15/2015
TE Code
AB1
On Market Since
6/17/2015
Pharmacological Classes
Price Statistics
The NADAC for CLONIDINE HCL ER 0.1 MG TABLET has been published 586 times since Jul 15, 2015, and over the history we have for it it has declined 93.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2117 per EA |
|---|---|
| All-time high | $3.4274 (Feb 10, 2016) |
| All-time low | $0.2005 (Nov 20, 2024) |
| 52-week high | $0.2846 |
| 52-week low | $0.2117 |
| Median price | $0.8144 |
| Average price | $1.3663 |
| Largest weekly change | +40.5% (Oct 20, 2021) |
| Weeks tracked | 586 |
| Tracking since | Jul 15, 2015 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 89% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
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Drug market
Clonidine Hydrochloride market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLONIDINE HCL ER 0.1 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CLONIDINE HCL ER 0.1 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.2117 per EA (NDC 00228424106), effective Sep 30, 2026.
How has the price of CLONIDINE HCL ER 0.1 MG TABLET changed over time?
Over the history we have for it, the NADAC for CLONIDINE HCL ER 0.1 MG TABLET has declined 93.7%. It has been tracked across 586 weekly CMS publications since Jul 15, 2015.
What are the highest and lowest recorded NADAC prices for CLONIDINE HCL ER 0.1 MG TABLET?
Since Jul 15, 2015, the NADAC for CLONIDINE HCL ER 0.1 MG TABLET has ranged from a low of $0.2005 (Nov 20, 2024) to a high of $3.4274 (Feb 10, 2016), with a median of $0.8144 per EA.
Are there cheaper alternatives to CLONIDINE HCL ER 0.1 MG TABLET?
Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLONIDINE HCL 0.1 MG TABLET, is $0.0241 per EA — about 89% below CLONIDINE HCL ER 0.1 MG TABLET.
Who manufactures CLONIDINE HCL ER 0.1 MG TABLET?
CLONIDINE HCL ER 0.1 MG TABLET (NDC 00228424106) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.