Product Information
MIDODRINE HCL 5 MG TABLET is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.1112 per EA under NDC 00245021201. Its NADAC has been published 657 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the midodrine hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
5 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
00245021201
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
MIDODRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076725On Market Since
11/3/2004
Pharmacological Classes
Price Statistics
The NADAC for MIDODRINE HCL 5 MG TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 72.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1112 per EA |
|---|---|
| All-time high | $0.7270 (Apr 15, 2015) |
| All-time low | $0.1084 (Feb 18, 2026) |
| 52-week high | $0.1503 |
| 52-week low | $0.1084 |
| Median price | $0.3997 |
| Average price | $0.3606 |
| Largest weekly change | +49.4% (Feb 18, 2015) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of MIDODRINE HCL 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MIDODRINE HCL 5 MG TABLET, manufactured by Upsher-Smith Laboratories LLC, is $0.1112 per EA (NDC 00245021201), effective Jun 24, 2026.
How has the price of MIDODRINE HCL 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for MIDODRINE HCL 5 MG TABLET has declined 72.3%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for MIDODRINE HCL 5 MG TABLET?
Since Nov 28, 2013, the NADAC for MIDODRINE HCL 5 MG TABLET has ranged from a low of $0.1084 (Feb 18, 2026) to a high of $0.7270 (Apr 15, 2015), with a median of $0.3997 per EA.
Are there cheaper alternatives to MIDODRINE HCL 5 MG TABLET?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, MIDODRINE HCL 5 MG TABLET, is $0.1084 per EA — about 2% below MIDODRINE HCL 5 MG TABLET.
Who manufactures MIDODRINE HCL 5 MG TABLET?
MIDODRINE HCL 5 MG TABLET (NDC 00245021201) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.
Related Drugs
Same classification