Product Information

TOSYMRA 10 MG NASAL SPRAY is a brand product labeled by Upsher-Smith Laboratories LLC, priced at $108.2212 per EA under NDC 00245081261. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Jan 25, 2019.

The High Outlier badge above means this manufacturer's average price in the sumatriptan market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

TOSYMRA 10 MG NASAL SPRAY

sumatriptan
$108.2212per EA
High Outlier

Strength

10 mg/.1mL

NDC

00245081261

Classification

Brand

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

SUMATRIPTAN

Approval Type

New Drug (NDA)

FDA Application

NDA210884

FDA Approved

1/25/2019

On Market Since

7/8/2019

Pharmacological Classes

Serotonin 1b Receptor Agonists
Serotonin 1d Receptor Agonists
Serotonin-1b and Serotonin-1d Receptor Agonist

Price Statistics

The NADAC for TOSYMRA 10 MG NASAL SPRAY has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 6.5%. The table below summarizes its recorded NADAC range and movement.

Current price$108.2212 per EA
All-time high$108.7802 (Mar 12, 2025)
All-time low$101.6129 (Apr 17, 2024)
52-week high$108.3932
52-week low$107.6342
Median price$108.1796
Average price$107.6464
Largest weekly change+6.4% (Jul 10, 2024)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+0.0%

1M

+0.0%

3M

+0.1%

6M

+0.4%

1Y

-0.2%

3Y

N/A

5Y

N/A

All

+6.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the sumatriptan market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of TOSYMRA 10 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for TOSYMRA 10 MG NASAL SPRAY, manufactured by Upsher-Smith Laboratories LLC, is $108.2212 per EA (NDC 00245081261), effective Aug 19, 2026.

How has the price of TOSYMRA 10 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for TOSYMRA 10 MG NASAL SPRAY has risen 6.5%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for TOSYMRA 10 MG NASAL SPRAY?

Since Apr 17, 2024, the NADAC for TOSYMRA 10 MG NASAL SPRAY has ranged from a low of $101.6129 (Apr 17, 2024) to a high of $108.7802 (Mar 12, 2025), with a median of $108.1796 per EA.

Are there cheaper alternatives to TOSYMRA 10 MG NASAL SPRAY?

No other NADAC-published product currently shares the active ingredient and strength of TOSYMRA 10 MG NASAL SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures TOSYMRA 10 MG NASAL SPRAY?

TOSYMRA 10 MG NASAL SPRAY (NDC 00245081261) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a brand product.